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Tarnasol (Losartan)
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Tarnasol

Tarnasol belongs to a group of medicines known as angiotensin-II receptor antagonists. Angiotensin-II is a substance produced in the body which binds to receptors in blood vessels, causing them to tighten. This results in an increase in blood pressure. Tarnasol prevents the binding of angiotensin-II to these receptors, causing the blood vessels to relax which in turn lowers the blood pressure. Tarnasol slows the decrease of kidney function in patients with high blood pressure and type 2 diabetes.

Other names for this medication:
Acetensa, Angioten, Arapres, Aratan, Cardzaar, Corodin, Cosart, Czartan, Eklips, Forzaar, Insaar, Klosartan, Lacine, Lepitrin, Loben, Loctenk, Lohyp, Loortan, Lorista, Losagen, Losakind, Losapres, Losar, Losartan, Losartec, Losartic, Lospre, Lostan, Lotar, Lozap, Lozatan, Myotan, Nefrotal, Osartil, Portiron, Sarilen, Sartaxal, Simperten, Sortiva, Tensaar, Tensartan, Tozaar, Zaart

Similar Products:
Microzide, Coreg, Moduretic, Cordarone, Lasix, Trandate, Lanoxin, Cozaar, Lozol

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Also known as: Losartan

Description

Tarnasol (losartan potassium) is an angiotensin II receptor blocker acting on the AT1 receptor subtype. Losartan potassium, a non-peptide molecule, is chemically described as 2-butyl-4-chloro-1-[p-(o-1Htetrazol- 5-ylphenyl)benzyl]imidazole-5-methanol monopotassium salt.

Tarnasol is a white to off-white free-flowing crystalline powder with a molecular weight of 461.01. It is freely soluble in water, soluble in alcohols, and slightly soluble in common organic solvents, such as acetonitrile and methyl ethyl ketone. Oxidation of the 5-hydroxymethyl group on the imidazole ring results in the active metabolite of losartan.

Tarnasol is available as tablets for oral administration containing either 25 mg, 50 mg or 100 mg of losartan potassium and the following inactive ingredients: microcrystalline cellulose, lactose hydrous, pregelatinized starch, magnesium stearate, hydroxypropyl cellulose, hypromellose, and titanium dioxide.

Tarnasol 25 mg, 50 mg and 100 mg tablets contain potassium in the following amounts: 2.12 mg (0.054 mEq), 4.24 mg (0.108 mEq) and 8.48 mg (0.216 mEq), respectively. Tarnasol 25 mg, Tarnasol 50 mg, and Tarnasol 100 mg may also contain carnauba wax.

Dosage

Take Tarnasol tablets orally with or without food. Do not crush or chew it. Take Tarnasol once or twice a day at the same time. If you want to achieve most effective results do not stop taking Tarnasol suddenly.

Overdose

If you overdose Tarnasol and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Tarnasol overdosage: fainting, feeling lightheaded, rapid heartbeat.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Tarnasol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Changes in renal function including acute renal failure can be caused by drugs that inhibit the reninangiotensin system and by diuretics. Patients whose renal function may depend in part on the activity of the renin-angiotensin system (e.g., patients with renal artery stenosis, chronic kidney disease, severe congestive heart failure, or volume depletion) may be at particular risk of developing acute renal failure on COZAAR. Monitor renal function periodically in these patients. Consider withholding or discontinuing therapy in patients who develop a clinically significant decrease in renal function on Tarnasol.

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Remote monitoring and follow-up of cardiovascular implantable electronic devices in the Netherlands : An expert consensus report of the Netherlands Society of Cardiology. Addition of deep brain stimulation signal to a local field potential driven Izhikevich model masks the pathological firing pattern of an STN neuron. Adjustments of haemocyanin physiological function and haemocyanin concentrations but also high dissolved oxygen concentrations support oxygen supply in the Antarctic octopus Pareledone charcoti at near freezing temperatures. Comparisons between experiments and calculations that account nonperturbatively for these quantum kinetic Coulomb correlations demonstrate large compensations between mean-field contributions and transitions to the two-pair continuum. Editorial: Genetics and epigenetics of fetal alcohol spectrum disorders. The primary route of spread appears to be via neuroglial cells rather than the axons. Under the assumption that after transfusion, the upper limit of the local resistance of a capillary should not surpass that in the same capillary of normal blood flow, critical hematocrit values with different exchange percentage rates are determined. Strain IHBB 10380 Using PacBio Single-Molecule Real-Time Sequencing Technology. In the second series of experiments, speciation of aluminium in situ was investigated using the ferron assay method. A new method, thermometric enzyme linked immunosorbent assay (TELISA), for the assay of endogenous and exogenous compounds in biological fluids is described.

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Sliding scale insulin is still the most common alternative to insulin regimen based on basal-bolus-correction scheduled insulin. Simultaneously to the strictly physical mechanisms of injury, such as direct compression of intra-abdominal organs and vessels, the transmission of IAP to other compartments, and the drop in cardiac output, a series of immune-inflammatory mediators generated in the intestine itself may also intervene. Seventy strains of the Burkholderia cepacia complex, which currently comprises six genomic species, were tested for their ability to produce N-acylhomoserine lactone (AHL) signal molecules. Mesenchymal stem cells (MSC) are a unique population of adult stem cells that have the capacity to differentiate into numerous cell types as well as the ability to modulate the immune system. Different responses of epicardium and endocardium to KATP channel modulators during regional ischemia. Two case reports are presented that describe epicardial and endocardial VT ablation performed during LVAD placement. The postnasal skin graft inlay was the most frequent procedure, and it seems best suited for these repairs in developing countries where the patients often present late with major deformities. The therapy of hibernating myocardium is to restore blood flow to the hypoperfused tissue. The linear presentation of the program may be used directly on the PC, or may be projected on a screen from the PC, for small classes or for a larger audience (200 persons). Considered together with other clinical and laboratory indices, these determinations may aid in the differential diagnosis of pleurisy of various etiology.

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(S025) discovery and validation of predictive factors for safety incident reports in patients receiving radiation therapy: comparative results from a large safety variance database. Safety of local anaesthesia induced by prilocaine with felypressin in patients on tricyclic antidepressants. The purpose of this study was to evaluate the thyroid cancer rate and analyze recent changes in the extent of thyroid cancer surgeries in Korea. Reliability analysis of a smartphone-aided measurement method for the Cobb angle of scoliosis. Anomalous muscle bundles in the right ventricle divide the right ventricle into two portions and cause intracavitary obstruction of the right ventricle. The patient felt pain free, whereas she did not receive anti-osteoporosis treatment after the surgery. Considerations using silver nitrate as a reference for in vitro tests with silver nanoparticles. However, a strong damping of toroidal rotation is observed as such plasmas approach marginal stability for perturbations that produce a kinklike distortion of the plasma.

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We investigated whether variants in other lysosomal storage disorder (LSD) genes also contribute to disease pathogenesis. Functional needs of subjects with dentofacial deformities: A study using the index of orthognathic functional treatment need (IOFTN). Immunochemical separation of apolipoprotein B-48-and B-100-containing lipoproteins. The torque in a heavy sphere limit agrees with a prior analysis by Busse and Wang using boundary flow analysis. Informing is not composed simply of conveying information, but also to elevate patients to a proficiency level where they could decide with their best interest. We will describe promising new approaches for the identification of aptamers targeting proteins with a crucial role in glioma, including SELEX protocols against living glioma cells and brain tumor-initiating cells. Parents and children having VP have less distress with parental presence. The Role of Gastroesophageal Reflux and Other Factors during Progression to Esophageal Adenocarcinoma. Comparing parecoxib and ketorolac as preemptive analgesia in patients undergoing posterior lumbar spinal fusion: a prospective randomized double-blinded placebo-controlled trial. amazonensis-enhancing factor and that the PKR/IFN1 axis and IL-10 are critical mediators of this IL-27 induced effect.

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Transplantation of a premolar to replace a central incisor with advanced resorption. The frequent gains of stress response among green algal duplicates potentially reflect a high rate of innovation, resulting in a species-specific gene repertoire that contributed to adaptive response to stress. An international review of all available data on elective orthopaedic surgery in inhibitor patients is required so that the optimal treatment regime can be defined and the short- and long-term risk-benefit ratio of surgery compared to that of noninhibitor patients. One hundred and forty-six women with singleton pregnancies, undergoing amniocentesis at the Department of Obstetrics and Gynaecology at the University Medical Centre Ljubljana, were prospectively enrolled. However, a high level of uncertainty is evident in the findings, and additional research may be useful. TIP, an integral membrane protein of the protein-storage vacuoles of the soybean cotyledon undergoes developmentally regulated membrane accumulation and removal. The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/7609324661510147. Experience with echographic investigation of the kidney and the urinary efferent system in the diagnosis of renal insufficiency is reported. T helper cell- and CD40-dependent germline IgM prevents chronic virus-induced demyelinating disease. Plant sterol oxides in functional beverages: influence of matrix and storage.

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Annual and seasonal home ranges were calculated for 47 Eurasian lynx in four Scandinavian study sites (two in Sweden and two in Norway). Of the 15 quality measures, only one has a statistically significant relationship with the MLR. In general, variables related to system responsiveness were more consistent predictors of receipt of aftercare than variables related to either client vulnerability or community support. Untreated diabetic animals exhibited hyperglycemia, hyperlipidemia, reduced growth, cardiomegaly, and hepatomegaly. After transformation into completent E.coli cells, the candidate clones were identified by PCR and kidney cell line 293T cells by lipofectamine 2000 to produce the lentiviral particles, and the viral titer was determined. Perforation of a gastric tube is a rare yet lethal complication after esophagectomy for esophageal cancer treatment. Flap endonuclease 1 (FEN1) plays critical roles in DNA replication and repair and in counteracting replication stress, which is a key mechanism for many chemotherapeutic drugs to kill cancer cells. The apomorphine treatments given to the vehicle group generated a progressive locomotion sensitization effect and this effect was potentiated by pre-exposure to 0.03 mg/kg haloperidol. In particular cases, methyl (Z)-3-(2,4-dichlorophenyl)-2-(thiocyanomethyl)-2-propenoate exhibited antimicrobial activity comparable to the reference antibiotic Imipenem. The nucleotide sequence of lambda phage clone 4121, which contains the 18.8 kb fragment of Saccharomyces cerevisiae chromosome VI left arm, was determined.

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The following research examined the associations between polymorphisms in these two genes and individual differences in emotional and cognitive empathy in a sample of 367 young adults. Immunohistochemical staining revealed the lesional cells to be actin- (3/3) and caldesmon- (2/3) positive and negative for other smooth muscle markers, compatible with perivascular myopericytic differentiation. Nuclear translocation of cytosolic phospholipase A2 is induced by ATP depletion. Nanoformulations need to systematically explored in future, for their new clinical role in prophylaxis of migraine attacks in children. Habanero fruit with three different doses (0.08, 0.05 and 0.025 g of dry matter (d.m.) habanero fruit/kg b.w.) in 2 equal doses every 12 hours during 28 days was administered intragastrically in male rats. Owing toGiven the high costs of drugs to treat multi-drug resistant tuberculosis (MDR-TB), the Green Light Committee (GLC) initiative enables TB programs to procure quality-assured drugs at reduced prices. High regeneration rates in anther culture of interspecific sunflower hybrids. The application of a precision medicine approach to the collaterome, a comprehensive synthesis of neurovascular pathophysiology, will entail novel methods for clinical trial randomization, collection of routine and clinical trial imaging results, data archiving, and analysis. Advanced malignant mesothelioma mimicking acute contained thoracic aortic rupture.

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