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Tarnasol (Losartan)

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Tarnasol belongs to a group of medicines known as angiotensin-II receptor antagonists. Angiotensin-II is a substance produced in the body which binds to receptors in blood vessels, causing them to tighten. This results in an increase in blood pressure. Tarnasol prevents the binding of angiotensin-II to these receptors, causing the blood vessels to relax which in turn lowers the blood pressure. Tarnasol slows the decrease of kidney function in patients with high blood pressure and type 2 diabetes.

Other names for this medication:
Acetensa, Angioten, Arapres, Aratan, Cardzaar, Corodin, Cosart, Czartan, Eklips, Forzaar, Insaar, Klosartan, Lacine, Lepitrin, Loben, Loctenk, Lohyp, Loortan, Lorista, Losagen, Losakind, Losapres, Losar, Losartan, Losartec, Losartic, Lospre, Lostan, Lotar, Lozap, Lozatan, Myotan, Nefrotal, Osartil, Portiron, Sarilen, Sartaxal, Simperten, Sortiva, Tensaar, Tensartan, Tozaar, Zaart

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Microzide, Coreg, Moduretic, Cordarone, Lasix, Trandate, Lanoxin, Cozaar, Lozol

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Also known as: Losartan


Tarnasol (losartan potassium) is an angiotensin II receptor blocker acting on the AT1 receptor subtype. Losartan potassium, a non-peptide molecule, is chemically described as 2-butyl-4-chloro-1-[p-(o-1Htetrazol- 5-ylphenyl)benzyl]imidazole-5-methanol monopotassium salt.

Tarnasol is a white to off-white free-flowing crystalline powder with a molecular weight of 461.01. It is freely soluble in water, soluble in alcohols, and slightly soluble in common organic solvents, such as acetonitrile and methyl ethyl ketone. Oxidation of the 5-hydroxymethyl group on the imidazole ring results in the active metabolite of losartan.

Tarnasol is available as tablets for oral administration containing either 25 mg, 50 mg or 100 mg of losartan potassium and the following inactive ingredients: microcrystalline cellulose, lactose hydrous, pregelatinized starch, magnesium stearate, hydroxypropyl cellulose, hypromellose, and titanium dioxide.

Tarnasol 25 mg, 50 mg and 100 mg tablets contain potassium in the following amounts: 2.12 mg (0.054 mEq), 4.24 mg (0.108 mEq) and 8.48 mg (0.216 mEq), respectively. Tarnasol 25 mg, Tarnasol 50 mg, and Tarnasol 100 mg may also contain carnauba wax.


Take Tarnasol tablets orally with or without food. Do not crush or chew it. Take Tarnasol once or twice a day at the same time. If you want to achieve most effective results do not stop taking Tarnasol suddenly.


If you overdose Tarnasol and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Tarnasol overdosage: fainting, feeling lightheaded, rapid heartbeat.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Tarnasol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Changes in renal function including acute renal failure can be caused by drugs that inhibit the reninangiotensin system and by diuretics. Patients whose renal function may depend in part on the activity of the renin-angiotensin system (e.g., patients with renal artery stenosis, chronic kidney disease, severe congestive heart failure, or volume depletion) may be at particular risk of developing acute renal failure on COZAAR. Monitor renal function periodically in these patients. Consider withholding or discontinuing therapy in patients who develop a clinically significant decrease in renal function on Tarnasol.

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Remote monitoring and follow-up of cardiovascular implantable electronic devices in the Netherlands : An expert consensus report of the Netherlands Society of Cardiology. Addition of deep brain stimulation signal to a local field potential driven Izhikevich model masks the pathological firing pattern of an STN neuron. Adjustments of haemocyanin physiological function and haemocyanin concentrations but also high dissolved oxygen concentrations support oxygen supply in the Antarctic octopus Pareledone charcoti at near freezing temperatures. Comparisons between experiments and calculations that account nonperturbatively for these quantum kinetic Coulomb correlations demonstrate large compensations between mean-field contributions and transitions to the two-pair continuum. Editorial: Genetics and epigenetics of fetal alcohol spectrum disorders. The primary route of spread appears to be via neuroglial cells rather than the axons. Under the assumption that after transfusion, the upper limit of the local resistance of a capillary should not surpass that in the same capillary of normal blood flow, critical hematocrit values with different exchange percentage rates are determined. Strain IHBB 10380 Using PacBio Single-Molecule Real-Time Sequencing Technology. In the second series of experiments, speciation of aluminium in situ was investigated using the ferron assay method. A new method, thermometric enzyme linked immunosorbent assay (TELISA), for the assay of endogenous and exogenous compounds in biological fluids is described.

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Sliding scale insulin is still the most common alternative to insulin regimen based on basal-bolus-correction scheduled insulin. Simultaneously to the strictly physical mechanisms of injury, such as direct compression of intra-abdominal organs and vessels, the transmission of IAP to other compartments, and the drop in cardiac output, a series of immune-inflammatory mediators generated in the intestine itself may also intervene. Seventy strains of the Burkholderia cepacia complex, which currently comprises six genomic species, were tested for their ability to produce N-acylhomoserine lactone (AHL) signal molecules. Mesenchymal stem cells (MSC) are a unique population of adult stem cells that have the capacity to differentiate into numerous cell types as well as the ability to modulate the immune system. Different responses of epicardium and endocardium to KATP channel modulators during regional ischemia. Two case reports are presented that describe epicardial and endocardial VT ablation performed during LVAD placement. The postnasal skin graft inlay was the most frequent procedure, and it seems best suited for these repairs in developing countries where the patients often present late with major deformities. The therapy of hibernating myocardium is to restore blood flow to the hypoperfused tissue. The linear presentation of the program may be used directly on the PC, or may be projected on a screen from the PC, for small classes or for a larger audience (200 persons). Considered together with other clinical and laboratory indices, these determinations may aid in the differential diagnosis of pleurisy of various etiology.

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(S025) discovery and validation of predictive factors for safety incident reports in patients receiving radiation therapy: comparative results from a large safety variance database. Safety of local anaesthesia induced by prilocaine with felypressin in patients on tricyclic antidepressants. The purpose of this study was to evaluate the thyroid cancer rate and analyze recent changes in the extent of thyroid cancer surgeries in Korea. Reliability analysis of a smartphone-aided measurement method for the Cobb angle of scoliosis. Anomalous muscle bundles in the right ventricle divide the right ventricle into two portions and cause intracavitary obstruction of the right ventricle. The patient felt pain free, whereas she did not receive anti-osteoporosis treatment after the surgery. Considerations using silver nitrate as a reference for in vitro tests with silver nanoparticles. However, a strong damping of toroidal rotation is observed as such plasmas approach marginal stability for perturbations that produce a kinklike distortion of the plasma.

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We investigated whether variants in other lysosomal storage disorder (LSD) genes also contribute to disease pathogenesis. Functional needs of subjects with dentofacial deformities: A study using the index of orthognathic functional treatment need (IOFTN). Immunochemical separation of apolipoprotein B-48-and B-100-containing lipoproteins. The torque in a heavy sphere limit agrees with a prior analysis by Busse and Wang using boundary flow analysis. Informing is not composed simply of conveying information, but also to elevate patients to a proficiency level where they could decide with their best interest. We will describe promising new approaches for the identification of aptamers targeting proteins with a crucial role in glioma, including SELEX protocols against living glioma cells and brain tumor-initiating cells. Parents and children having VP have less distress with parental presence. The Role of Gastroesophageal Reflux and Other Factors during Progression to Esophageal Adenocarcinoma. Comparing parecoxib and ketorolac as preemptive analgesia in patients undergoing posterior lumbar spinal fusion: a prospective randomized double-blinded placebo-controlled trial. amazonensis-enhancing factor and that the PKR/IFN1 axis and IL-10 are critical mediators of this IL-27 induced effect.

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Transplantation of a premolar to replace a central incisor with advanced resorption. The frequent gains of stress response among green algal duplicates potentially reflect a high rate of innovation, resulting in a species-specific gene repertoire that contributed to adaptive response to stress. An international review of all available data on elective orthopaedic surgery in inhibitor patients is required so that the optimal treatment regime can be defined and the short- and long-term risk-benefit ratio of surgery compared to that of noninhibitor patients. One hundred and forty-six women with singleton pregnancies, undergoing amniocentesis at the Department of Obstetrics and Gynaecology at the University Medical Centre Ljubljana, were prospectively enrolled. However, a high level of uncertainty is evident in the findings, and additional research may be useful. TIP, an integral membrane protein of the protein-storage vacuoles of the soybean cotyledon undergoes developmentally regulated membrane accumulation and removal. The virtual slide(s) for this article can be found here: Experience with echographic investigation of the kidney and the urinary efferent system in the diagnosis of renal insufficiency is reported. T helper cell- and CD40-dependent germline IgM prevents chronic virus-induced demyelinating disease. Plant sterol oxides in functional beverages: influence of matrix and storage.

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Annual and seasonal home ranges were calculated for 47 Eurasian lynx in four Scandinavian study sites (two in Sweden and two in Norway). Of the 15 quality measures, only one has a statistically significant relationship with the MLR. In general, variables related to system responsiveness were more consistent predictors of receipt of aftercare than variables related to either client vulnerability or community support. Untreated diabetic animals exhibited hyperglycemia, hyperlipidemia, reduced growth, cardiomegaly, and hepatomegaly. After transformation into completent E.coli cells, the candidate clones were identified by PCR and kidney cell line 293T cells by lipofectamine 2000 to produce the lentiviral particles, and the viral titer was determined. Perforation of a gastric tube is a rare yet lethal complication after esophagectomy for esophageal cancer treatment. Flap endonuclease 1 (FEN1) plays critical roles in DNA replication and repair and in counteracting replication stress, which is a key mechanism for many chemotherapeutic drugs to kill cancer cells. The apomorphine treatments given to the vehicle group generated a progressive locomotion sensitization effect and this effect was potentiated by pre-exposure to 0.03 mg/kg haloperidol. In particular cases, methyl (Z)-3-(2,4-dichlorophenyl)-2-(thiocyanomethyl)-2-propenoate exhibited antimicrobial activity comparable to the reference antibiotic Imipenem. The nucleotide sequence of lambda phage clone 4121, which contains the 18.8 kb fragment of Saccharomyces cerevisiae chromosome VI left arm, was determined.

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The following research examined the associations between polymorphisms in these two genes and individual differences in emotional and cognitive empathy in a sample of 367 young adults. Immunohistochemical staining revealed the lesional cells to be actin- (3/3) and caldesmon- (2/3) positive and negative for other smooth muscle markers, compatible with perivascular myopericytic differentiation. Nuclear translocation of cytosolic phospholipase A2 is induced by ATP depletion. Nanoformulations need to systematically explored in future, for their new clinical role in prophylaxis of migraine attacks in children. Habanero fruit with three different doses (0.08, 0.05 and 0.025 g of dry matter (d.m.) habanero fruit/kg b.w.) in 2 equal doses every 12 hours during 28 days was administered intragastrically in male rats. Owing toGiven the high costs of drugs to treat multi-drug resistant tuberculosis (MDR-TB), the Green Light Committee (GLC) initiative enables TB programs to procure quality-assured drugs at reduced prices. High regeneration rates in anther culture of interspecific sunflower hybrids. The application of a precision medicine approach to the collaterome, a comprehensive synthesis of neurovascular pathophysiology, will entail novel methods for clinical trial randomization, collection of routine and clinical trial imaging results, data archiving, and analysis. Advanced malignant mesothelioma mimicking acute contained thoracic aortic rupture.

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We present a case of a 19-year-old woman with no significant medical history who presented with progressive changes in mental status and profound ictal asystole that necessitated the placement of an external temporary pacemaker. Northern blot analysis of unstimulated PAEC and PMVEC with porcine-specific probes reveals constitutive expression of B7-2 mRNA while B7-1 message was not detected. Patients with cholangiocarcinoma had extended mean stent patency of 19.5 months (range, 2-46 months) and mean survival of 22. calan cost 6 months (range, 2-72 months). Regression and inhibition of sarcoma growth by interference with a radiosensitive T-cell population. Muscle-evoked potentials of hind limbs after electrical stimulation to the brain were recorded in some of the recovered rats, but never in the unrecovered rats. Immune response to antituberculosis drug-loaded gelatin and polyisobutyl-cyanoacrylate nanoparticles in macrophages. The axons of these intrapancreatic nerves appear to terminate only in the islet tissue and not on any exocrine components of the explant.

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Recent conflicting reports on OCT4 expression in tumor cells and tissues emphasize the need to discriminate the expression of OCT4A from other variants as well as OCT4 pseudogenes. The type of vitamin D supplementation, whether cholecalciferol or ergocalciferol, was documented. Change in the Positive and norvasc dose range Negative Syndrome Scale (PANSS) was analyzed using both observed case (OC) and last observation carried forward (LOCF) analyses. To make this clearer, this peri-gastrulating period is described herein with a focus on its main developmental landmarks, and the resilience of the landmarks in the face of biotechnologies is questioned. Although, negative results were obtained for all viruses considered, the high proportion of Hyalomma ticks highlights the potential risk for the dissemination of tick-borne viruses through infested migratory birds. Intensity dependence of cation kinetic energies from 2,5-dihydroxybenzoic acid near the infrared matrix-assisted laser desorption/ionization threshold. Apical root resorption does occur more readily in these teeth before, during, and after orthodontic treatment. Salmonella enterica flagellin is recognized via FLS2 and activates PAMP-triggered immunity in Arabidopsis thaliana. Understanding the microscopic mechanisms for LQT1 needs a global view of the I(Ks) channel. Production, optimization and characterization of polyhydroxybutyrate, a biodegradable plastic by Bacillus spp.

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Lastly, EPAs could increase transparency in the workplace regarding student abilities and help ensure safe and quality patient care. This study compares the amount of head movement in American football, lacrosse, and ice hockey helmets during head and neck stabilization procedures. Released monomers were analyzed by reversed-phase liquid chromatography at UV 210 nm. Control of sand flies with attractive toxic sugar baits (ATSB) and potential impact on non-target organisms in Morocco. Phenotypic drift inBradyrhizobium japonicum populations after introduction into soils as established by numerical analysis. However, the association of plasma fibronectin with atrial remodelling has not been studied previously.

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Alginate is a linear polymer of beta-1, 4-linked L-guluronic acid and D-mannuronic acid. Tailored CVD graphene coating as a transparent and flexible gas barrier. We conducted a 15-year (2000-2014) retrospective chart review of the radiologic, pathologic, clinical management, and recurrence rates of patients with PLCIS on diagnostic biopsy. However, it is difficult to assess the frequency, duration, type and intensity of PA. Laparoscopic liver resection can be considered a safe procedure for the treatment of liver tumors. The congenital disorders were classified in 3 groups of malformation: ventral induction disorders, cortical malformations, and congenital malformations of the posterior fossa. Regional haemodynamic effects of antagonists of angiotensin II, endothelin and adrenoceptors in conscious, vasopressin-deficient, genetically hypertensive rats. The understanding of pain by older adults who consider themselves to have aged successfully.

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Hemochromatosis, an iron-overload disease, occurs as adult and juvenile types. Assessing risk of hospital readmissions for improving medical practice. GM-CSF failed to reduce significantly the cumulative hematological toxicity of chemotherapy and zidovudine. TPM can be used to detect significant differences in LV torsion in patients with reduced EF and in the presence of local wall motion abnormalities. The effect of the introduction of a regional major trauma network on triage decisions made by a physician-staffed helicopter emergency medical service. The results suggest that this system enables the detection of SB episodes at home with considerably high accuracy and little interference with sleep. Moreover, the amino acid residues inferred to form the surface of the binding-site crevice based adalat medication class on our application of the substituted-cysteine accessibility method in the dopamine D(2) receptor are in remarkable agreement with the rhodopsin structure, with the notable exception of some residues in the fourth transmembrane segment.

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The decision to return to play following an ankle injury is a multifactorial process involving both physical and psychological parameters. A 5-year-old girl diagnosed with biotinidase deficiency at 9 months of age demonstrated limb and axial hypotonia which improved on biotin therapy. The use of orthosis did not influence the kyphosis angulation in subjects with stable fracture in thoracolumbar spine. We investigated the effect of human and rat Gal and substituted analogues of Gal on the contractility of longitudinal muscle strips of the human colon in vitro. Using the Dynamic Vessel Analyzer in patients with RVO, we found that intravitreal ranibizumab increased vein side effects of bystolic medication dilation (dynamic analysis) and had a vasoconstrictive effect on both arteries and veins (static analysis). Correlation between Cortical State and Locus Coeruleus Activity: Implications for Sensory Coding in Rat Barrel Cortex. Results showed no statistically significant differences between the two agents.

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Self-assembly of multicomponent anisotropic nanocrystals with controlled orientation and spatial distribution allows the design of novel metamaterials with unique shape- and orientation-dependent collective properties. CpG islands (CGIs), central to the regulation of mammalian gene expression, are exceptional in terms of whether, when and how they are affected by epigenetic reprogramming. A rate kinetic model has been used to understand the time dependence of the yield of the product acid. Three homologous nitrogenases have been identified to date, along with several structural and/or functional homologs of this enzyme that are involved in nitrogenase assembly, bacteriochlorophyll biosynthesis and methanogenic process, respectively. Primary versus secondary delayed gastric emptying (DGE) grades B and C of the International Study Group of Pancreatic Surgery after pancreatoduodenectomy: a retrospective analysis on a group of 132 patients. A regularized relaxed ordered subset list-mode reconstruction algorithm and its preliminary application to undersampling PET imaging. Janus kinases have so far been viewed as enzymatic intermediates that couple a variety of cell surface receptors to downstream substrates with diverse effector functions. Chloroesters were obtained as the depolymerization products, which are suitable precursors for new polymers. The creation of peripheral lymphovenous anastomoses with a moderate long-term patency rate has become technically possible.

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Stent placement for upper and lower bowel obstructions is an option in nonoperable patients. Following treatment, aSAH patients and meningioma patients experience poorer subjective sleep and some differences in objectively measured sleep, which might be attributable to increased sleep-related dysfunctional cognitions and poorer overall psychological functioning. The results reported here indicate that 1) the NBM activation of both GABA(A) and GABA(B) receptors influences the sleep/wake cycle, and 2) GABA(A) but not GABA(B) receptors are important for desynchronized sleep modulation, suggesting that the two GABAergic receptors play different roles in sleep modulation. The six cases of the literature were clinically, biologically and epidemiologically similar. Ranolazine in combination with low dose dronedarone remarkably reduced AF-burden in the phase II HARMONY trial. Among the countries with a population of 5 million or less, the highest incidence was observed in Croatia (46 cases per year, peritoneal tumors not included). Fitness equivalence is no longer guaranteed by a perfect trade-off, and contrary to popular belief, dispersal limitation is found to impede rather than facilitate the stochastic coexistence of species. Inhibition of transformation and transfection in Haemophilus influenzae Rd9 by lysogeny. Ischemic preconditioning and pretreatment with CGRP for 5 min significantly improved cardiac function and reduced CK release during reperfusion at 2 and 6 months of age but not at 20 months of age.

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