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Synerpril (Amiloride)
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Synerpril

Synerpril is in a class of medications called diuretics. It works by causing the kidneys to get rid of unneeded water and salt from the body into the urine, but reduces the loss of potassium.

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Also known as: Amiloride

Description

Synerpril is a diuretic (water pill) and a combination of a potassium-sparing diuretic (amiloride) and a thiazide diuretic (hydrochlorothiazide). It works by making the kidneys eliminate sodium (salt) and water from the body, which helps to lower blood pressure. The amiloride component helps minimize potassium loss. Brand name of Synerpril is Synerpril.

Dosage

Take Synerpril by mouth with food. Synerpril may increase the amount of urine or cause you to urinate more often when you first start taking it. To keep this from disturbing your sleep, try to take your dose before 6 pm. If you want to achieve most effective results do not stop taking Synerpril suddenly.

Overdose

If you overdose Synerpril and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Do not freeze. Keep container closed tightly. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Synerpril are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Synerpril if you are allergic to Synerpril components or to any ingredient in Synerpril or any other sulfonamide (eg, sulfamethoxazole). Be careful with Synerpril if you're pregnant or you plan to have a baby, or you are a nursing mother. Be careful with Synerpril if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement. Be careful with Synerpril if you have allergies to medicines, foods, or other substances. Be careful with Synerpril if you have cirrhosis or liver problems, diabetes, gout, kidney problems or kidney stones, asthma, heart problems, or systemic lupus erythematosus. Be careful with Synerpril if you have elevated blood acid, low folic acid levels, or electrolyte problems, or are dehydrated. Be careful with Synerpril if you take potassium-sparing diuretics (eg, spironolactone), potassium supplements, or salt substitutes containing potassium because high blood potassium levels may occur and cause listlessness, confusion, abnormal skin sensations of the arms and legs, heaviness of limbs, slowed heart rate, irregular heart rhythm, or stopping of the heart; cholestyramine or colestipol because they may decrease Synerpril 's effectiveness; nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, indomethacin) because they may decrease Synerpril 's effectiveness and risk of kidney problems may be increased; barbiturates (eg, phenobarbital), certain chemotherapy medicines, corticosteroids (eg, prednisone), digoxin, dofetilide, ketanserin, narcotic pain medicines (eg, codeine), or medicines for high blood pressure because the risk of their side effects may be increased by Synerpril; diazoxide, lithium, or nondepolarizing neuromuscular blockers (eg, pancuronium) because their actions and the risk of their side effects may be increased by Synerpril; angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril) because the risk of high blood potassium and kidney problems may be increased by Synerpril; diabetes medicines (eg, glipizide) or insulin because their effectiveness may be decreased by Synerpril. Do not stop taking Synerpril suddenly.

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