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Sarlo (Losartan)
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Sarlo

Sarlo and associated names, 12,5 mg, 25mg, 50 mg, 100 mg, film-coated tablets is an orally active angiotensin II (Ang- II) receptor antagonist, Sarlo, acting on the AT1 receptor subtype, thus blocking the effect of Ang-II in the renin angiotensin system (RAS) cascade. Sarlo is indicated for the treatment of hypertension.

Other names for this medication:
Angilock, Angioten, Biortan, Cardzaar, Cartan, Corus, Czartan, Faxiven, Forzaar, Gitox, Klosartan, Loben, Loplac, Losadel, Losagen, Losap, Losarb, Losartic, Losatan, Lostad, Lotim, Loxibin, Maxartan, Myotan, Osartan, Osartil, Sanipresin, Sartaxal, Sartens, Sarvastan, Tensaar, Tiasar, Xartan

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Also known as: Losartan

Description

Sarlo (losartan potassium) is an angiotensin II receptor blocker acting on the AT1 receptor subtype. Losartan potassium, a non-peptide molecule, is chemically described as 2-butyl-4-chloro-1-[p-(o-1Htetrazol- 5-ylphenyl)benzyl]imidazole-5-methanol monopotassium salt.

Sarlo is a white to off-white free-flowing crystalline powder with a molecular weight of 461.01. It is freely soluble in water, soluble in alcohols, and slightly soluble in common organic solvents, such as acetonitrile and methyl ethyl ketone. Oxidation of the 5-hydroxymethyl group on the imidazole ring results in the active metabolite of losartan.

Sarlo is available as tablets for oral administration containing either 25 mg, 50 mg or 100 mg of losartan potassium and the following inactive ingredients: microcrystalline cellulose, lactose hydrous, pregelatinized starch, magnesium stearate, hydroxypropyl cellulose, hypromellose, and titanium dioxide.

Sarlo 25 mg, 50 mg and 100 mg tablets contain potassium in the following amounts: 2.12 mg (0.054 mEq), 4.24 mg (0.108 mEq) and 8.48 mg (0.216 mEq), respectively. Sarlo 25 mg, Sarlo 50 mg, and Sarlo 100 mg may also contain carnauba wax.

Dosage

Take Sarlo tablets orally with or without food. Do not crush or chew it. Take Sarlo once or twice a day at the same time. If you want to achieve most effective results do not stop taking Sarlo suddenly.

Overdose

If you overdose Sarlo and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Sarlo overdosage: fainting, feeling lightheaded, rapid heartbeat.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Sarlo are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Sarlo if you are allergic to Sarlo components. Do not take Sarlo if you're pregnant or you plan to have a baby, or you are a nursing mother. Sarlo can harm your baby. Do not use Sarlo if you are taking salt substitutes or potassium supplements, other blood pressure medicine, diuretic (water pill). It can be dangerous to use Sarlo if you suffer from or have a history of liver disease, kidney disease, heart failure. If you want to achieve most effective results without any side effects it is better to avoid alcohol. Avoid machine driving. Do not stop taking Sarlo suddenly.

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IgG4-related disease (IgG4-RD) is a chronic systemic disease involved in many organs and tissues. Cranial irradiation in children with lymphoblastic acute leukemia: results and damages. The paraflagellar bodies (PFBs) of isolated flagella ofEuglena gracilis were investigated microspectrophotometrically using a visible- and infrared-light microscope with image analyzer and microspectrophotometer. In this setting occupancy of the receptors with a muscarinic antagonist was without detectable effect on any of the muscarinic oligomers. TRC) was determined by histopathology or by clinical/MRI-follow-up. Nurse faculty experiences in problem-based learning: an interpretive phenomenologic analysis. Reabsorption of unusual appearance is seen around the Haversian canals. Ambulation in spinal cord injured patients--options: where do we stand?. Sequencing of a 4.3 kbp region of chromosome 2 of Candida albicans reveals the presence of homologues of SHE9 from Saccharomyces cerevisiae and of bacterial phosphatidylinositol-phospholipase C.

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Experiments were also carried out to determine expression of the C-type lectin Dectin-2 receptor. Inverse associations were demonstrated between DMFT and total calcium, phosphorus, magnesium, strontium, potassium, and fluoride concentrations in individual plaques. A tau peptide encompassing the epitope revealed by DC8E8 was selected for the development of an active vaccine targeting structural determinants on mis-disordered tau protein that are essential for pathological tau-tau interaction. Intravenous immunoglobulin therapy in the treatment of BK viremia and nephropathy in pediatric renal transplant recipients. A Low Dimensional Approximation For Competence In Bacillus Subtilis. The purpose of this article is to present possible explanations. Greater verbal comprehension deficits were noted in children with atypical receptive language representation, a risk factor for cognitive morbidity. Implicit memory was evidenced at test by faster entry of the old than the new numbers, regardless of whether the numbers were in the same or different format, suggesting that the abstract numerical meaning, not the surface form, contributes to repetition priming.

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These results suggest that particular efforts should be made to bridge the significant gap between the pace of nursing practice transformation and the objectives of service integration. Conducting polymers of a Schiff-base ligand and the corresponding oxo-vanadium(IV) complex have been synthesized, characterized, and studied. Furthermore, we demonstrated a positive correlation between Id1 and phospho-Akt expression in SGC-7901 cells. The main purpose of this study is to compare affective temperaments between Argentinean professional tango dancers and the general population. The results of the carbohydrate-inhibition tests indicate that the lectin specificities in Phlebotomus are similar to those in Lutzomyia. Although ADSCs seem more promising for regenerative application generally, BMSCs may represent a better choice for treating bone disorders. However, further investigations are needed in the future to reduce or eliminate its toxicities before developing into new drug. We propose a novel method called Gibbs sampler to Infer Signal Transduction pathways (GIST) to search dys-regulated pathways from large-scale protein-protein interaction networks.

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Off-site movement of endosulfan from irrigated cotton in New South Wales. Of all the correlates of resistance, one appears to be of special interest: natural killer (NK) activity. Thirty-three consecutive oblique closing base wedge osteotomies of the first metatarsal bone are evaluated. Inflammation plays an integral role in carcinogenesis and tumor progression. Design modification and optimisation of the perfusion system of a tri-axial bioreactor for tissue engineering. A model for the interaction of wheat monomeric and dimeric protein inhibitors with alpha-amylase. It has not yet been investigated that NSCs relate to the recurrence and prognosis in various cancers. A comparision of 11beta-hydroxylase activity and specificity for different steroid substrates by possum (Trichosurus vulpecula), kangaroo (Macropus major) and beef. This study looks at direct influences of family SES and SES-age interactions (exposure-dependent CAD mechanisms), as well as indirect influences through SES-linked youth experiences (path-dependent CAD mechanisms) to explain variations in SES-based inequality. Recently, major attention has been paid to the role of hypoglycemia as a cardiovascular risk factor.

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International Standard Randomised Controlled Trial Number Register 12723675. The results suggest that DSI may potentially be useful to assist the pre-surgical evaluation in patients with intractable epilepsy. As compared to SAPHO syndrome, skin lesions and chest wall involvement are less common in CRMO. Key questions regarding the feasibility of using ClC-2 as a therapeutic target are addressed in the present studies, including whether the channels are present in human lung epithelia and whether activators of the channel can be identified. VA-using women tend to have different and greater medical needs than those having children. Variability in whole-cell biocatalyst performance represents a critical aspect for stable and productive bioprocessing. To evaluate and compare image quality between flat-panel volumetric computed tomography (fpVCT) and multislice CT (msCT) in temporal bones with cochlear implants (CIs), and to evaluate fpVCT imaging for accuracy in determining CI electrode positioning. Immunohistochemical studies of neo-urothelium revealed EGFP-positive cells expressing the urothelial markers K7 and UP3. Clinical Model for NASH and Advanced Fibrosis in Adult Patients With Diabetes and NAFLD: Guidelines for Referral in NAFLD.

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