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Repace (Losartan)

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Repace and associated names, 12,5 mg, 25mg, 50 mg, 100 mg, film-coated tablets is an orally active angiotensin II (Ang- II) receptor antagonist, Repace, acting on the AT1 receptor subtype, thus blocking the effect of Ang-II in the renin angiotensin system (RAS) cascade. Repace is indicated for the treatment of hypertension.

Other names for this medication:
Asart, Cardoplus, Cormac, Cosart, Cozaarex, Czartan, Faxiven, Fortzaar, Forzaar, Giovax, Hizaar, Lacine, Loben, Loortan, Losapot, Losapres, Losargamma, Losartax, Losartec, Losartic, Losartil, Losatrix, Losavik, Lostankal, Lozar, Lyosan, Maxartan, Mozartan, Osartan, Osartil, Portiron, Sanipresin, Sortiva, Tacicul, Tanlozid, Tarnasol, Tensaar, Tensiohess, Tiasar, Zaart

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Also known as: Losartan


Repace (losartan potassium) is an angiotensin II receptor blocker acting on the AT1 receptor subtype. Losartan potassium, a non-peptide molecule, is chemically described as 2-butyl-4-chloro-1-[p-(o-1Htetrazol- 5-ylphenyl)benzyl]imidazole-5-methanol monopotassium salt.

Repace is a white to off-white free-flowing crystalline powder with a molecular weight of 461.01. It is freely soluble in water, soluble in alcohols, and slightly soluble in common organic solvents, such as acetonitrile and methyl ethyl ketone. Oxidation of the 5-hydroxymethyl group on the imidazole ring results in the active metabolite of losartan.

Repace is available as tablets for oral administration containing either 25 mg, 50 mg or 100 mg of losartan potassium and the following inactive ingredients: microcrystalline cellulose, lactose hydrous, pregelatinized starch, magnesium stearate, hydroxypropyl cellulose, hypromellose, and titanium dioxide.

Repace 25 mg, 50 mg and 100 mg tablets contain potassium in the following amounts: 2.12 mg (0.054 mEq), 4.24 mg (0.108 mEq) and 8.48 mg (0.216 mEq), respectively. Repace 25 mg, Repace 50 mg, and Repace 100 mg may also contain carnauba wax.


Take Repace tablets orally with or without food. Do not crush or chew it. Take Repace once or twice a day at the same time. If you want to achieve most effective results do not stop taking Repace suddenly.


If you overdose Repace and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Repace overdosage: fainting, feeling lightheaded, rapid heartbeat.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Changes in renal function including acute renal failure can be caused by drugs that inhibit the reninangiotensin system and by diuretics. Patients whose renal function may depend in part on the activity of the renin-angiotensin system (e.g., patients with renal artery stenosis, chronic kidney disease, severe congestive heart failure, or volume depletion) may be at particular risk of developing acute renal failure on COZAAR. Monitor renal function periodically in these patients. Consider withholding or discontinuing therapy in patients who develop a clinically significant decrease in renal function on Repace.

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To clarify the relationship between colonization of periodontopathic bacteria and cytokines, we evaluated profiles of inflammatory cytokines, chemokine, anti-inflammatory cytokines, and inducible nitric oxide synthase (iNOS) and colonization by Porphyromonas gingivalis and Actinobacillus actinomycetemcomitans, which are major pathogens of periodontitis. Intrahepatic cholangiocarcinoma (ICC) is a highly aggressive tumor of the bile duct, and a significant public health problem in East Asia, where it is associated with infection by the parasite Opisthorchis viverrini. There is no evidence that any one regimen is associated with fewer side-effects. The status of large vessels in overweight and obesity according to ultrasound findings. Precise localization of human beta-globin gene complex on chromosome 11. Indeed, AMDE-1 triggered necroptosis and was preferentially cytotoxic to cancer cells. Three-dimensional feather like bayerite/boehmite nanocomposites were synthesized by a facile one-pot hydrothermal method. According to literature data this histological type of the gastrointestinal lymphoma has poor response to chemotherapy, the prognosis is unfavourable. We here used two different RNA-seq datasets, de novo transcriptome assemblies, homology-based comparisons, and trained ab initio gene callers to generate a new gene annotation of Z.

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Distinction was made between lesion type, location, and procedural sedation and analgesic (PSA). Evaluation of a multiplex real time reverse transcription PCR assay for the detection and quantitation of the most common human rotavirus genotypes. Patient demographics, Lund-Mackay computed tomography (CT) scores, 22-item Sino-Nasal Outcome Test (SNOT-22) scores, disease characteristics, and medication use were collected prior to FESS. Breast reduction is a common procedure used to improve physical and aesthetic factors associated with breast hypertrophy. Factors affecting synonymous codon usage bias in chloroplast genome of oncidium gower ramsey. Recently evolving health care systems including prescriptions should use these findings obtained from the study. Variability, heritability and association of some morpho-agronomic traits in field pea (Pisum sativum L.) genotypes. We excluded PUNLMP diagnosed after a previous or with a concurrent urothelial neoplasm. This reduced working memory capacity led to a pronounced increase in reaction time and errors when mental addition was performed concurrently with a memory load task.

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In this randomized, controlled crossover clinical study of 20 chronic pain patients, Cryoslide significantly reduced perceived pain compared to the baseline and the control group. open appendectomy for acute appendicitis: A double-blind randomized study. In addition, in randomized trials using H(2)-receptor antagonists, there was no reduction in re-bleeding and mortality. Overexpression of AtADF1 resulted in the disappearance of thick actin cables in different cell types, caused irregular cellular and tissue morphogenesis, and reduced the growth of cells and organs. To determine the impact of postoperative AF (POAF) on long-term outcome in a large cohort of patients who underwent CABG. An increase in the total phenolic content over time did not correlate with an observed, highly elevated antioxidant capacity (AOC) in the blood plasma after apple juice consumption. The Hard Stop required telephone contact with the laboratory and justification to have the duplicate test performed, whereas the Smart Alert allowed the provider to bypass the alert at the point of order entry without justification.

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In vitro simulation research on the hoop stress of myocardial bridge--coronary artery. Autophagy plays a role as a specialized immunologic effector and regulates innate immunity to exert antimicrobial defense mechanisms. The effect of acculturation is minimal when older adults have supportive families and good health. - a volume obtained after applying a Gaussian distribution and a morphological top-hat filter to the input and b. We also used multiple regression to explore whether the severity of premonitory urges was predicted by interoceptive awareness or severity of tics and obsessive-compulsive symptoms. Economic environment and education background were the main factors affecting menarcheal age, and menarcheal age may be considered as a predictor of adult obesity. Comparison between linear and star-like HPMA conjugated pirarubicin (THP) in pharmacokinetics and antitumor activity in tumor bearing mice. Correlation between mean body mass index in the population and prevalence of obesity in Brazilian capitals: empirical evidence for a population-based approach of obesity. A novel application of radiomimetic compounds as antibiotic drugs.

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Its ability to be easily propagated and its high phenotypic variability make it an ideal model system for functional, ecological and evolutionary genetics. Confidential illness reports were completed by all individuals with symptoms of AGI, and samples of fecal matter and vomitus, surface swabs of rafting equipment, and environmental swabs at stops along the hiking corridor were collected and tested for the presence of norovirus using reverse transcription-quantitative polymerase chain reaction (RT-qPCR). jejuni isolates were grouped by random amplification of polymorphic DNA (RAPD) profiling. This norvasc pill image finding, while reassuring, does not exclude the possibility of more subtle deficits. Recent experiments have showed that state-of-the-art descriptors provide better performances on the far-infrared (FIR) spectrum than on the visible one, even in daytime conditions, for pedestrian classification. The transformed base plan was used as the computed plan for each femur. The simulation results clearly show that the proposed CSB-II method is robust to sensing noise. Percutaneous sacroiliac screw for unstable type C 1-2 hip bone fracture: about a case at the University Hospital of Yaounde.

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If the material is allowed to set longer, the percentage change in compression moduretic 25/2 5 mg set decreases. As has been observed in water, the number of bdellovibrios in sediment fluctuated, with seasonal and temperature changes declining to very low numbers during the winter months. Endothelial dysfunction present in patients with peripheral artery disease may be better understood by measuring the temporal dynamics of blood flow and oxygen saturation during reactive hyperemia than by conventional static measurements. Because of its low incidence little is known about treatment outcomes. Effect of prazosin on blood pressure and plasma renin activity in man. Histopathological findings following root filling with zinc oxide-eugenol.

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The ability to reliably distinguish synchronous primary non-small-cell lung cancer (NSCLC) from intrapulmonary metastatic spread affects staging and treatment decisions in resected NSCLC. The reported methodology has great potential for further optimization into a new standard method for fast and accurate surface energy determination, and hence provides a new tool for reservoir rock wettability characterization. Quantitative analysis of the number, normal and pathologic ratios between lymphocytes and epithelial cells (ECs), and the significance of intraepithelial lymphocytes (IELs) in normal prostatic epithelium, benign prostatic hyperplasia (BPH), and high grade prostatic intraepithelial neoplasia (PIN) in relation to NIH category IV prostatitis (histologic prostatitis: HP) was studied in autopsy prostate. Overall, the prevailing pattern is that there are few commonalities between the genomes of independently evolved parasitic worms, with each parasite having undergone specific adaptations for their particular niche. T and B lymphocytes in patients with steroid-dependent bronchial asthma during long-term treatment. A significant number of research groups across Europe share the common objective, yet in conspicuously individual ways, of utilizing such polymers for devising innovative biomedical tools and techniques.

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The patient had an uneventful recovery and was discharged home on the 4th postoperative day. The review aims at elucidating the role of lipid peroxidation of polyunsaturated fatty acids (PUFAs) in colorectal cancer (CRC) risk and treatment. In this cordarone 200 mg effets secondaires study, we investigated the natural nodulation of legume forage crops were widely grown in the natural pastures in Sanliurfa, Turkey. These genes, numbering several hundreds or even thousands, control a vital but highly redundant system. First an anisotropic concentric cylinder model of the electric field intra-body communication for human limbs was developed based on the galvanic method. Response of intestinal globule leucocytes in the mouse during a Trichinella spiralis infection and its independence of intestinal mast cells.

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We aimed to give voice to how healthcare workers in two East African hospitals identify and explain the major obstacles to ensuring the safety of patients in their care. To determine the correlation among the clinical characteristics of pruritus, psoriasis scalp severity index (PSSI), and intraepidermal nerve fiber (IENF) density in psoriatic scalp lesions. The proliferating mesenchymal cells surrounding the epithelia of the efferent ductules have arranged in several concentric layers at about 85 days. The reconstruction of extensive femoral defects, particularly septic, by revascularized free fibula flap has become part of routine practice for many years. Thus, while decreased bioavailability probably plays a role in the protection seen after i.p. FMD viral RNA isolation, cDNA synthesis, and polymerase chain reaction were performed calan 120 mg to synthesize expression cassettes (P1-2AB3BC(wt) and P1-2AB3BC(m)) followed by cloning in pShuttle-CMV vector.

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