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Nefrotal (Losartan)

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Nefrotal is a hypertension treatment. Research suggests that the medication is safe and effective for most people. People may experience mild side effects, such as dizziness, in the early stages of treatment. People who experience severe or persistent side effects should contact their doctor right away.

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Also known as: Losartan


Nefrotal (losartan potassium) is an angiotensin II receptor blocker acting on the AT1 receptor subtype. Losartan potassium, a non-peptide molecule, is chemically described as 2-butyl-4-chloro-1-[p-(o-1Htetrazol- 5-ylphenyl)benzyl]imidazole-5-methanol monopotassium salt.

Nefrotal is a white to off-white free-flowing crystalline powder with a molecular weight of 461.01. It is freely soluble in water, soluble in alcohols, and slightly soluble in common organic solvents, such as acetonitrile and methyl ethyl ketone. Oxidation of the 5-hydroxymethyl group on the imidazole ring results in the active metabolite of losartan.

Nefrotal is available as tablets for oral administration containing either 25 mg, 50 mg or 100 mg of losartan potassium and the following inactive ingredients: microcrystalline cellulose, lactose hydrous, pregelatinized starch, magnesium stearate, hydroxypropyl cellulose, hypromellose, and titanium dioxide.

Nefrotal 25 mg, 50 mg and 100 mg tablets contain potassium in the following amounts: 2.12 mg (0.054 mEq), 4.24 mg (0.108 mEq) and 8.48 mg (0.216 mEq), respectively. Nefrotal 25 mg, Nefrotal 50 mg, and Nefrotal 100 mg may also contain carnauba wax.


Take Nefrotal tablets orally with or without food. Do not crush or chew it. Take Nefrotal once or twice a day at the same time. If you want to achieve most effective results do not stop taking Nefrotal suddenly.


If you overdose Nefrotal and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Nefrotal overdosage: fainting, feeling lightheaded, rapid heartbeat.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Nefrotal are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Nefrotal if you are allergic to Nefrotal components. Do not take Nefrotal if you're pregnant or you plan to have a baby, or you are a nursing mother. Nefrotal can harm your baby. Do not use Nefrotal if you are taking salt substitutes or potassium supplements, other blood pressure medicine, diuretic (water pill). It can be dangerous to use Nefrotal if you suffer from or have a history of liver disease, kidney disease, heart failure. If you want to achieve most effective results without any side effects it is better to avoid alcohol. Avoid machine driving. Do not stop taking Nefrotal suddenly.

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