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Nefrix (Amiloride)
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Nefrix

Nefrix is a potassium-sparing diuretic (water pill) that helps your body to retain potassium, unlike other water pills. It doesn't have a huge effect on lowering your blood pressure, but it does help to restore potassium levels and prevent low potassium levels that can be caused by other water pills taken for high blood pressure or congestive heart failure.

Other names for this medication:
Angiozide, Bifrizide, Bisoplus, Bpzide, Briazide, Cibadrex, Cilazil, Cosaar, Dehydratin, Ditenside, Diurace, Drenol, Duradiuret, Dytide, Enacecor, Epratenz, Eprosartan, Esidrex, Esidrix, Fosicomb, Fozide, Foziretic, Hexazide, Hydrozide, Hypodehydra, Hypothiazid, Lispirl, Nefrix, Nephral, Oretic, Pantemon, Quinaretic, Renacor, Rofucal, Synerpril, Tevetec, Triamizide, Triamteril, Wytens, Zoprazide

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Also known as: Amiloride

Description

Nefrix is a diuretic (water pill) and a combination of a potassium-sparing diuretic (amiloride) and a thiazide diuretic (hydrochlorothiazide). It works by making the kidneys eliminate sodium (salt) and water from the body, which helps to lower blood pressure. The amiloride component helps minimize potassium loss. Brand name of Nefrix is Nefrix.

Dosage

Take Nefrix by mouth with food. Nefrix may increase the amount of urine or cause you to urinate more often when you first start taking it. To keep this from disturbing your sleep, try to take your dose before 6 pm. If you want to achieve most effective results do not stop taking Nefrix suddenly.

Overdose

If you overdose Nefrix and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Do not freeze. Keep container closed tightly. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Nefrix are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Nefrix if you are allergic to Nefrix components or to any ingredient in Nefrix or any other sulfonamide (eg, sulfamethoxazole). Be careful with Nefrix if you're pregnant or you plan to have a baby, or you are a nursing mother. Be careful with Nefrix if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement. Be careful with Nefrix if you have allergies to medicines, foods, or other substances. Be careful with Nefrix if you have cirrhosis or liver problems, diabetes, gout, kidney problems or kidney stones, asthma, heart problems, or systemic lupus erythematosus. Be careful with Nefrix if you have elevated blood acid, low folic acid levels, or electrolyte problems, or are dehydrated. Be careful with Nefrix if you take potassium-sparing diuretics (eg, spironolactone), potassium supplements, or salt substitutes containing potassium because high blood potassium levels may occur and cause listlessness, confusion, abnormal skin sensations of the arms and legs, heaviness of limbs, slowed heart rate, irregular heart rhythm, or stopping of the heart; cholestyramine or colestipol because they may decrease Nefrix 's effectiveness; nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, indomethacin) because they may decrease Nefrix 's effectiveness and risk of kidney problems may be increased; barbiturates (eg, phenobarbital), certain chemotherapy medicines, corticosteroids (eg, prednisone), digoxin, dofetilide, ketanserin, narcotic pain medicines (eg, codeine), or medicines for high blood pressure because the risk of their side effects may be increased by Nefrix; diazoxide, lithium, or nondepolarizing neuromuscular blockers (eg, pancuronium) because their actions and the risk of their side effects may be increased by Nefrix; angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril) because the risk of high blood potassium and kidney problems may be increased by Nefrix; diabetes medicines (eg, glipizide) or insulin because their effectiveness may be decreased by Nefrix. Do not stop taking Nefrix suddenly.

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Lithium Sulfide (Li2S)/Graphene Oxide Nanospheres with Conformal Carbon Coating as a High-Rate, Long-Life Cathode for Li/S Cells. In the study, elimination of NTHi strains isolated from healthy and carrier individuals, varying with several genetic determinants, from mice nasopharynx, lungs and ears tissues and the interactions among strains during mixed infections were evaluated. Some of the experimental and clinical aspects of the effects of the maternal diabetes on developing hippocampus. Interestingly, in vivo MDSC what is the generic version of bystolic targeting by anti-GR1 antibodies and 5-Fluorouracil resulted in a significant reduced tumor load in 5TMM-diseased mice. Between the ages of 14 and 18, the proportion of girls wanting to be thinner increased, although it remained unchanged among boys. After operation, the patient received S-1 oral monotherapy(100mg/day for 28 days, followed by 14 days of rest)for 3 years. SOX10 mutation with peripheral amyelination and developmental disturbance of axons. Addition of putrescine was required for auxin responsive transient gene expression in rolA protoplasts suggesting that polyamines, or their products affect gene expression in rolA plants. Women who undergo mitral surgery for organic MR receive similar repair for similar degenerative lesions defined by echocardiography and enjoy similar survival and reverse cardiac remodeling, but they incur excess post-operative heart failure linked to worse pre-operative presentation. Dermal fibroblasts induce cell cycle arrest and block epithelial-mesenchymal transition to inhibit the early stage melanoma development.

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