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Losartil (Losartan)
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Losartil

Losartil belongs to a group of drugs called angiotensin II receptor antagonists (sometimes called ARB blockers). It keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow. Losartil is used to treat high blood pressure (hypertension) in adults and children who are at least 6 years old. It is also used to lower the risk of stroke in certain people with heart disease.

Other names for this medication:
Angibloc, Arapres, Asart, Cormac, Cosart, Covance, Czartan, Forzaar, Klosartan, Lacine, Loben, Loctenk, Losadel, Losagen, Losapot, Losartas, Losartil, Losatrix, Losazid, Losazide, Lostat, Lotar, Lozatan, Myotan, Omnitan, Prelow, Resilo, Sarvastan, Sarve, Temisartan, Tensaar, Tensartan, Zaart

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Also known as: Losartan

Description

Losartil (losartan potassium) is an angiotensin II receptor blocker acting on the AT1 receptor subtype. Losartan potassium, a non-peptide molecule, is chemically described as 2-butyl-4-chloro-1-[p-(o-1Htetrazol- 5-ylphenyl)benzyl]imidazole-5-methanol monopotassium salt.

Losartil is a white to off-white free-flowing crystalline powder with a molecular weight of 461.01. It is freely soluble in water, soluble in alcohols, and slightly soluble in common organic solvents, such as acetonitrile and methyl ethyl ketone. Oxidation of the 5-hydroxymethyl group on the imidazole ring results in the active metabolite of losartan.

Losartil is available as tablets for oral administration containing either 25 mg, 50 mg or 100 mg of losartan potassium and the following inactive ingredients: microcrystalline cellulose, lactose hydrous, pregelatinized starch, magnesium stearate, hydroxypropyl cellulose, hypromellose, and titanium dioxide.

Losartil 25 mg, 50 mg and 100 mg tablets contain potassium in the following amounts: 2.12 mg (0.054 mEq), 4.24 mg (0.108 mEq) and 8.48 mg (0.216 mEq), respectively. Losartil 25 mg, Losartil 50 mg, and Losartil 100 mg may also contain carnauba wax.

Dosage

Take Losartil tablets orally with or without food. Do not crush or chew it. Take Losartil once or twice a day at the same time. If you want to achieve most effective results do not stop taking Losartil suddenly.

Overdose

If you overdose Losartil and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Losartil overdosage: fainting, feeling lightheaded, rapid heartbeat.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Losartil are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Losartil if you are allergic to Losartil components. Do not take Losartil if you're pregnant or you plan to have a baby, or you are a nursing mother. Losartil can harm your baby. Do not use Losartil if you are taking salt substitutes or potassium supplements, other blood pressure medicine, diuretic (water pill). It can be dangerous to use Losartil if you suffer from or have a history of liver disease, kidney disease, heart failure. If you want to achieve most effective results without any side effects it is better to avoid alcohol. Avoid machine driving. Do not stop taking Losartil suddenly.

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