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Losapot (Losartan)
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Losapot

Losapot is a medication mainly used to treat high blood pressure. It is also used for diabetic kidney disease, heart failure, and left ventricular enlargement. It is taken by mouth. It may be used alone or in addition to other blood pressure medication.

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Also known as: Losartan

Description

Losapot (losartan potassium) is an angiotensin II receptor blocker acting on the AT1 receptor subtype. Losartan potassium, a non-peptide molecule, is chemically described as 2-butyl-4-chloro-1-[p-(o-1Htetrazol- 5-ylphenyl)benzyl]imidazole-5-methanol monopotassium salt.

Losapot is a white to off-white free-flowing crystalline powder with a molecular weight of 461.01. It is freely soluble in water, soluble in alcohols, and slightly soluble in common organic solvents, such as acetonitrile and methyl ethyl ketone. Oxidation of the 5-hydroxymethyl group on the imidazole ring results in the active metabolite of losartan.

Losapot is available as tablets for oral administration containing either 25 mg, 50 mg or 100 mg of losartan potassium and the following inactive ingredients: microcrystalline cellulose, lactose hydrous, pregelatinized starch, magnesium stearate, hydroxypropyl cellulose, hypromellose, and titanium dioxide.

Losapot 25 mg, 50 mg and 100 mg tablets contain potassium in the following amounts: 2.12 mg (0.054 mEq), 4.24 mg (0.108 mEq) and 8.48 mg (0.216 mEq), respectively. Losapot 25 mg, Losapot 50 mg, and Losapot 100 mg may also contain carnauba wax.

Dosage

Take Losapot tablets orally with or without food. Do not crush or chew it. Take Losapot once or twice a day at the same time. If you want to achieve most effective results do not stop taking Losapot suddenly.

Overdose

If you overdose Losapot and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Losapot overdosage: fainting, feeling lightheaded, rapid heartbeat.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Losapot are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Losapot if you are allergic to Losapot components. Do not take Losapot if you're pregnant or you plan to have a baby, or you are a nursing mother. Losapot can harm your baby. Do not use Losapot if you are taking salt substitutes or potassium supplements, other blood pressure medicine, diuretic (water pill). It can be dangerous to use Losapot if you suffer from or have a history of liver disease, kidney disease, heart failure. If you want to achieve most effective results without any side effects it is better to avoid alcohol. Avoid machine driving. Do not stop taking Losapot suddenly.

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Acrokeratosis Verruciformis of Hopf Clinically Mimicking Epidermodysplasia Verruciformis. Critical challenges remain including biomaterials capable of matching the mechanical properties and extracellular matrix (ECM) composition of neural tissues, compartmentalized scaffolds that support heterogeneous tissue architectures reflective of brain organization and structure, and robust functional assays for in vitro tissue validation. Hox homeobox transcription factors drive leukemogenesis efficiently only in the presence of Meis or Pbx proteins. Comparison of three treatment regimens with liposomal amphotericin B (AmBisome) for visceral leishmaniasis in India: a randomized dose-finding study. Thus, this projection pattern strengthens the view that different compartments in the SC are involved in the control of gaze and in the control or modulation of reaching movements.

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In this issue of Blood, Fujikawa et al demonstrate that the human T-cell leukemia virus type 1 (HTLV-1) oncoprotein Tax induces an epigenetic-dependent global modification of host gene expression in adult T-cell leukemia-lymphoma (ATL). In each heart, 200 nuclear lengths and myocyte diameters, 160 fields for nuclear density, 420 fields for interstitial fibrosis and 350 fields for replacement fibrosis were evaluated. Recent studies showed that SCD has the ability to reprogram cardiac metabolism, thereby regulating heart function. We undertook a systematic review and meta-analysis of reported symptomatic, functional, and sexual outcomes following the PUL procedure. It is shown that the fractions separated in such wedge retain their rectilinear shape. A global energy active contour is then jointly defined over the entire video sequence, and the full glottal boundary is detected throughout the video via standard energy minimization. Comparative evaluation of the accumulation of bacterial plaque on human enamel and on the surfaces of various materials used for esthetic fillings. In spite of importance of caffeine effects on Korean adolescents, there are lack of scientific and systematic studies. A 2-minute intravenous injection of daptomycin in this patient yielded a reaction that was not present on rechallenge with standard, extended infusion. For many older people the emergency department was an appropriate place to attend considering their condition, though some presentations could be circumvented with appropriate and increased services in the community.

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It cannot be stated whether muscle pattern alterations seen in this study are coincidental with the dental and skeletal changes or vice versa. Student t tests were used to investigate differences in epithelial thickness, immunohistochemical staining of CD45, and inflammatory and profibrotic gene expression between vocal folds undergoing microflap and control. For assessing alcohol outcomes at shorter follow-ups, there were no differences between delivery modality. Loss of mTOR signaling affects cone function, cone structure and expression of cone specific proteins without affecting cone survival. doi: 10.1002/wrna.1351 For further resources related to this article, please visit the WIREs website.

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Spontaneous hypertensive rats were treated for 28 consecutive days and the blood pressure was measured weekly. Thirty two patients with newly diagnosed active pulmonary tuberculosis and 34 patients with inactive pulmonary tuberculosis were examined. Metabolic and kidney disorders correlate with high atazanavir concentrations in HIV-infected patients: is it time to revise atazanavir dosages?. The system was exchanged to the second one 42 hours after the surgery. The body image perception will condition the search of ideal beauty through different behaviors and can be transform in eating disorders. However, they are not sufficiently equipped to perform advanced laparoscopic procedures without supervision. Here we demonstrate that alkylation of methionine introduces a charge change that shifts the mobility of the protein on an acidic gel relative to diovan medication brand the alkylation-resistant sulfoxide form. Using a c-fos-based transgenic mouse, we found that contextual fear extinction silenced basal amygdala (BA) excitatory neurons that had been previously activated during fear conditioning. Trials with fewer than 100 flexible sigmoidoscopy screenings were excluded. Besides, the bioinhibition of MMP-9 may partially contribute to the neuroprotective effect.

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