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Losapot (Losartan)

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Losapot is a medication mainly used to treat high blood pressure. It is also used for diabetic kidney disease, heart failure, and left ventricular enlargement. It is taken by mouth. It may be used alone or in addition to other blood pressure medication.

Other names for this medication:
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Also known as: Losartan


Losapot (losartan potassium) is an angiotensin II receptor blocker acting on the AT1 receptor subtype. Losartan potassium, a non-peptide molecule, is chemically described as 2-butyl-4-chloro-1-[p-(o-1Htetrazol- 5-ylphenyl)benzyl]imidazole-5-methanol monopotassium salt.

Losapot is a white to off-white free-flowing crystalline powder with a molecular weight of 461.01. It is freely soluble in water, soluble in alcohols, and slightly soluble in common organic solvents, such as acetonitrile and methyl ethyl ketone. Oxidation of the 5-hydroxymethyl group on the imidazole ring results in the active metabolite of losartan.

Losapot is available as tablets for oral administration containing either 25 mg, 50 mg or 100 mg of losartan potassium and the following inactive ingredients: microcrystalline cellulose, lactose hydrous, pregelatinized starch, magnesium stearate, hydroxypropyl cellulose, hypromellose, and titanium dioxide.

Losapot 25 mg, 50 mg and 100 mg tablets contain potassium in the following amounts: 2.12 mg (0.054 mEq), 4.24 mg (0.108 mEq) and 8.48 mg (0.216 mEq), respectively. Losapot 25 mg, Losapot 50 mg, and Losapot 100 mg may also contain carnauba wax.


Take Losapot tablets orally with or without food. Do not crush or chew it. Take Losapot once or twice a day at the same time. If you want to achieve most effective results do not stop taking Losapot suddenly.


If you overdose Losapot and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Losapot overdosage: fainting, feeling lightheaded, rapid heartbeat.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Losapot are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Losapot if you are allergic to Losapot components. Do not take Losapot if you're pregnant or you plan to have a baby, or you are a nursing mother. Losapot can harm your baby. Do not use Losapot if you are taking salt substitutes or potassium supplements, other blood pressure medicine, diuretic (water pill). It can be dangerous to use Losapot if you suffer from or have a history of liver disease, kidney disease, heart failure. If you want to achieve most effective results without any side effects it is better to avoid alcohol. Avoid machine driving. Do not stop taking Losapot suddenly.

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Strain differences in Echinococcus granulosus, with special reference to the status of equine hydatidosis in the United Kingdom. Whether incident GI bleeding is also a marker of other GI cancers remains unclear. Furthermore, despite their small number, such synapses enable the network to respond faster and with more stability in the face of external fluctuations. Conservative treatments are usually successful, and spontaneous remission has been observed. In addition, evidence of micrographia likely adds to the literature on the localization of this finding.

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Acrokeratosis Verruciformis of Hopf Clinically Mimicking Epidermodysplasia Verruciformis. Critical challenges remain including biomaterials capable of matching the mechanical properties and extracellular matrix (ECM) composition of neural tissues, compartmentalized scaffolds that support heterogeneous tissue architectures reflective of brain organization and structure, and robust functional assays for in vitro tissue validation. Hox homeobox transcription factors drive leukemogenesis efficiently only in the presence of Meis or Pbx proteins. Comparison of three treatment regimens with liposomal amphotericin B (AmBisome) for visceral leishmaniasis in India: a randomized dose-finding study. Thus, this projection pattern strengthens the view that different compartments in the SC are involved in the control of gaze and in the control or modulation of reaching movements.

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Spontaneous hypertensive rats were treated for 28 consecutive days and the blood pressure was measured weekly. Thirty two patients with newly diagnosed active pulmonary tuberculosis and 34 patients with inactive pulmonary tuberculosis were examined. Metabolic and kidney disorders correlate with high atazanavir concentrations in HIV-infected patients: is it time to revise atazanavir dosages?. The system was exchanged to the second one 42 hours after the surgery. The body image perception will condition the search of ideal beauty through different behaviors and can be transform in eating disorders. However, they are not sufficiently equipped to perform advanced laparoscopic procedures without supervision. Here we demonstrate that alkylation of methionine introduces a charge change that shifts the mobility of the protein on an acidic gel relative to diovan medication brand the alkylation-resistant sulfoxide form. Using a c-fos-based transgenic mouse, we found that contextual fear extinction silenced basal amygdala (BA) excitatory neurons that had been previously activated during fear conditioning. Trials with fewer than 100 flexible sigmoidoscopy screenings were excluded. Besides, the bioinhibition of MMP-9 may partially contribute to the neuroprotective effect.

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Second-site suppression of regulatory phosphorylation in Escherichia coli isocitrate dehydrogenase. The competitive interaction between blue tits and great tits has shifted in one of the studied sites, creating conditions that alter the relative equilibrium densities between the two species, potentially disrupting long-term coexistence. Chelerythrine did not affect baseline perfusion pressure in the normoxic animal, whereas it lowered pulmonary vascular tone in chronically hypoxic animals. An intertypic recombinant virus was constructed and evaluated in animal models of zebeta tablet recurrent ocular and genital herpes. The therapeutic effect of many anticoagulants is not readily measured, so preoperatively, the surgeon cannot know the true risk for postoperative hemorrhage. To overcome this problem, we utilize tetraphenylethene-triphenylphosphonium (TPE-TPP), which possesses aggregation-induced emission (AIE) and two-photon fluorescence characteristics, for neuroimaging. The subclavian veins are the optimal sites for phrenic nerve stimulation.

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Expression of a neuroendocrine gene signature in gastric tumor cells from CEA 424-SV40 large T antigen-transgenic mice depends on SV40 large T antigen. DNA immunization as a technology platform for monoclonal antibody induction. Autophagy: from structure to metabolism to therapeutic regulation. Predisposing factors include chronic illness, underlying joint disease, joint trauma, and respiratory infection. The enriched OCLs cultured for 24 h on dentine slices formed only a few resorption pits. 1,25-dihydroxyvitamin D3 regulates the development of chronic colitis by modulating both T helper (Th)1 and Th17 activation. These data will provide a clear understanding of gene expression patterns associated with the gonadal development-related genes of this bisoprolol brand name in pakistan gynogenic teleost.

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