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Loben (Losartan)

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Loben belongs to a group of drugs called angiotensin II receptor antagonists (sometimes called ARB blockers). It keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow. Loben is used to treat high blood pressure (hypertension) in adults and children who are at least 6 years old. It is also used to lower the risk of stroke in certain people with heart disease.

Other names for this medication:
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Also known as: Losartan


Loben (losartan potassium) is an angiotensin II receptor blocker acting on the AT1 receptor subtype. Losartan potassium, a non-peptide molecule, is chemically described as 2-butyl-4-chloro-1-[p-(o-1Htetrazol- 5-ylphenyl)benzyl]imidazole-5-methanol monopotassium salt.

Loben is a white to off-white free-flowing crystalline powder with a molecular weight of 461.01. It is freely soluble in water, soluble in alcohols, and slightly soluble in common organic solvents, such as acetonitrile and methyl ethyl ketone. Oxidation of the 5-hydroxymethyl group on the imidazole ring results in the active metabolite of losartan.

Loben is available as tablets for oral administration containing either 25 mg, 50 mg or 100 mg of losartan potassium and the following inactive ingredients: microcrystalline cellulose, lactose hydrous, pregelatinized starch, magnesium stearate, hydroxypropyl cellulose, hypromellose, and titanium dioxide.

Loben 25 mg, 50 mg and 100 mg tablets contain potassium in the following amounts: 2.12 mg (0.054 mEq), 4.24 mg (0.108 mEq) and 8.48 mg (0.216 mEq), respectively. Loben 25 mg, Loben 50 mg, and Loben 100 mg may also contain carnauba wax.


Take Loben tablets orally with or without food. Do not crush or chew it. Take Loben once or twice a day at the same time. If you want to achieve most effective results do not stop taking Loben suddenly.


If you overdose Loben and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Loben overdosage: fainting, feeling lightheaded, rapid heartbeat.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Loben are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Use of drugs that act on the renin-angiotensin system during the second and third trimesters of pregnancy reduces fetal renal function and increases fetal and neonatal morbidity and death. Resulting oligohydramnios can be associated with fetal lung hypoplasia and skeletal deformations. Potential neonatal adverse effects include skull hypoplasia, anuria, hypotension, renal failure, and death. When pregnancy is detected, discontinue Loben as soon as possible.

In patients with an activated renin-angiotensin system, such as volume- or salt-depleted patients (e.g., those being treated with high doses of diuretics), symptomatic hypotension may occur after initiation of treatment with Loben. Correct volume or salt depletion prior to administration of Loben.

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Effect of processing on the nutrients and anti-nutrients of lima bean (Phaseolus lunatus L.) flour. Horseradish peroxidase (HRP) staining of the entire optic nerve showed a denervated region at the injection site with beaded, degenerating fibers at its edge. Considering our study results, prognostic implication of PRL should be questioned. GFP-C17.2 neural stem cells (NSCs) were transplanted into the subretinal space to study the immunomodulatory and neuroprotective effects. Most studies have been Phase I type, small numbers of subjects in acute (short-term) treatment situations. Aldosterone and the kidney: a rapidly moving frontier (an update). Ultrasound-Guided Diffuse Optical Tomography for Predicting and Monitoring Neoadjuvant Chemotherapy of Breast Cancers: Recent Progress. During follow-up, no significant changes in shape, dimension and appearance were observed. One-stitch anastomosis through the skin with bicanalicular intubation: a modified approach for repair of bicanalicular laceration. The accurate prediction of outcome after out-of-hospital cardiac arrest (OHCA) is of major importance.

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The berothid affinity of this genus is confirmed by examination of the hind wing venation characteristic of the family. High pressure induced charge transfer in 3d-4f bimetallic photomagnetic materials. This method was applied in selected eukaryotic proteomes, in order to examine the characteristics they exhibit in various eukaryotic kingdoms and phyla. Together, the present results suggest that the mechanical inflammatory nociceptor sensitization is dependent on glutamate release at the DRG and subsequent NMDAR activation in satellite glial cells, supporting the idea that the peripheral hyperalgesia is an event modulated by a glutamatergic system in the DRG. The length of strongylid nematode infective larvae as a reflection of developmental conditions in faeces and consequences on their viability. DNA origami has received enormous attention for its ability to program complex nanostructures with a few nanometer precision. Accordingly, antidepressants are generally suggested to reverse stress-induced structural changes augmenting dendritic arborisation and synaptogenesis.

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Electrocardiographic diagnosis of left circumflex artery occlusion and the occlusion site. The extensive use of the Emla cream largely contributed to reduce pain. We postulate that this may be based on an interaction at the level of the relevant cortico-thalamo-cortical circuit(s). Some studies show magnesium has analgesic effect in some pain models but this evaluation was not carried on nano-magnesium oxide (MgO). Patients and controls of both sexes, Caucasians and non-Caucasians, matched by sex, geographical origin and ethnicity were evaluated. Hypergeometric analysis of tiling-array and sequence data: detection and interpretation of peaks. Challenges to ultrasound-guided interventions arise, however, due to the low signal-to-noise ratio and the imaging artifacts created by the interventional instruments. It would be desirable to explore the causal relationship between SWD and multiple hypnotics use in a future longitudinal study.

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The effect of formaldehyde, hydrogen peroxide and genetic detoxification of pertussis toxin on epitope recognition inderal 10 mg tablet uses in marathi by murine monoclonal antibodies. The value of L/N on BSGI was independently related to infiltration degree and tumor size of breast cancer, but not to expression of tumor receptor markers and histologic grade. Recent genomic studies using next-generation sequencers have revealed recurrent genetic alterations implicated in CLL pathogenesis. Feasibility study of a sensor-based autonomous load control exercise training system for COPD patients. The emergence and increasing prevalence of resistant pathogens primarily in intensive care units demand the discovery and development of new antimicrobial agents and new therapeutic approaches.

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The aim of this study was to explore systemic influences on decision making by paramedics relating to care transitions to identify potential risk factors. The tumor locations were the distal femur in 31 cases, proximal femur in 11 cases, proximal tibia in 13 cases, distal radius in 6 cases, proximal humerus in 5 cases and proximal fibula in 5 cases. A common origin for woody Sonchus and five related genera in the Macaronesian islands: molecular evidence for extensive radiation. Sentence contexts were either constraining or nonconstraining toward the final word, presented as a picture. Apelin Enhances Brown Adipogenesis and Browning of White Adipocytes. Females were found to have consistently higher cell proliferation and cell surface marker expression. Harnessing the potential of the Kinect sensor for psychiatric rehabilitation for stroke survivors.

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Cytogenetic experiments in Drosophila have shown that HP1 localization into this chromatin is perturbed in mutants for the origin recognition complex (ORC) 2 subunit. These data support the reliability and validity of this method of assessing infectious illnesses. To describe patterns of smoking and smoking cessation in China within the context of the stages of change model, using data from the 1996 national prevalence survey. Rats were intragastrically administered IGs (50, 100 or 200 mg/ kg) twice daily for 3 days. In order to minimize patient exposure to DEHP, Taxol solutions should be prepared and administered in PVC-free materials. There was rapid settling of the exudative detachment and enalapril 2 5 mg para que sirve improvement in vision when the patient received chemotherapy. The study of diet among ethnic groups may be more informative than among populations with homogeneous diets. Children drew themselves and their friend standing significantly closer together and adults rated their drawings as more affiliative overall.

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Alkylindole-sensitive receptors modulate microglial cell migration and proliferation. JEMs are particularly useful in situations when information on psychosocial job stressors were not collected individually and can help eliminate the biases that may be present in individual self-report accounts. The mechanism apparently differs in various conditions predisposing to gallstone formation. Our study demonstrated that both cluster 1 and 2 anammox bacteria play an moduretic tablets active role in the CRD-OMZ, and the cluster 1 abundance and transcriptional activity were higher than cluster 2 in both free-living and particle-attached fractions at both gene and transcriptional levels. Cytoplasmic motility was inhibited in a dose-dependent manner by CaM antagonists. A 57-year-old patient was admitted to the Gynecology and Obstetrics Unit, Brothers of Mercy Hospital in Katowice for hysterectomy with bilateral salpingo-oophorectomy due to uterine myomata. These effects involved GIPC inhibition of the ERK1/2/JNK pathway. Calbindin-D28K is increased in the ventral horn of spinal cord by neuroprotective factors for motor neurons. Complete genome sequence of bovine papillomavirus genotype 13 from local yellow cattle in hainan province, china.

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