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Lepitrin (Losartan)
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Lepitrin

Lepitrin belongs to a class of drugs called angiotensin receptor blockers (ARBs). It works by relaxing blood vessels so that blood can flow more easily. It is taken by mouth. It may be used alone or in addition to other blood pressure medication.

Other names for this medication:
Anreb, Cardoplus, Corodin, Covance, Cozzar, Eklips, Faxiven, Fensartan, Giovax, Gitox, Hizaar, Klosartan, Lakea, Lepitrin, Lifezar, Loben, Loctenk, Losacar, Losacor, Losadel, Losagen, Losan, Losapres, Losarb, Losart, Losartan, Losartas, Losartax, Losartec, Losium, Lotar, Loxibin, Portiron, Psycholanz, Resilo, Sartaxal, Sarvas, Sarvastan, Sortal, Tacardia, Tacicul, Tarnasol, Temisartan, Zartan

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Also known as: Losartan

Description

Lepitrin is indicated for the treatment of hypertension in adults and pediatric patients 6 years of age and older, to lower blood pressure. Lowering blood pressure lowers the risk of fatal and nonfatal cardiovascular (CV) events, primarily strokes and myocardial infarction. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes including losartan.

Control of high blood pressure should be part of comprehensive cardiovascular risk management, including, as appropriate, lipid control, diabetes management, antithrombotic therapy, smoking cessation, exercise, and limited sodium intake. Many patients will require more than 1 drug to achieve blood pressure goals. For specific advice on goals and management

Lepitrin is indicated to reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy, but there is evidence that this benefit does not apply to Black patients

Lepitrin is indicated for the treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria in patients with type 2 diabetes and a history of hypertension. In this population, Lepitrin reduces the rate of progression of nephropathy as measured by the occurrence of doubling of serum creatinine or end stage renal disease

Dosage

Take Lepitrin tablets orally with or without food. Do not crush or chew it. Take Lepitrin once or twice a day at the same time. If you want to achieve most effective results do not stop taking Lepitrin suddenly.

Overdose

If you overdose Lepitrin and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Lepitrin overdosage: fainting, feeling lightheaded, rapid heartbeat.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Lepitrin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Changes in renal function including acute renal failure can be caused by drugs that inhibit the reninangiotensin system and by diuretics. Patients whose renal function may depend in part on the activity of the renin-angiotensin system (e.g., patients with renal artery stenosis, chronic kidney disease, severe congestive heart failure, or volume depletion) may be at particular risk of developing acute renal failure on COZAAR. Monitor renal function periodically in these patients. Consider withholding or discontinuing therapy in patients who develop a clinically significant decrease in renal function on Lepitrin.

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The plasma HDL levels in WHHL rabbits were inversely associated with high levels of plasma rEL proteins and hepatic expression of rEL mRNA. We investigated whether the addition of a citric acid/trisodium citrate (CA/TSC) mixture before extrusion increases iron absorption in humans from FePP-fortified extruded rice grains. Liver Transplantation for Hepatocellular Carcinoma: A Single Center Resume Overlooking Four Decades of Experience. However, the application of sealants (composed of two essential components: fibrinogen and thrombin) is not without difficulties. In the group of patients with severe mental disorder, medication review seems to provide a good opportunity to assess the rationality of pharmacotherapy in a multidisciplinary approach.

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