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Lasix (Furosemide)
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Lasix

Lasix is a loop diuretic medication used to treat fluid build-up due to heart failure, liver scarring, or kidney disease. It may also be used for the treatment of high blood pressure. It can be taken by injection into a vein or by mouth.

Other names for this medication:
Aldalix, Anfuramide, Ansemid, Betasemid, Foliront, Frusemide, Frusenex, Furantral, Furesis, Furetic, Furide, Furocot, Furosemide, Furovet, Furoxem, Furozenol, Fursemid, Furtenk, Fusix, Inclens, Intermed, Jufurix, Lasilacton, Lasilactone, Lasiletten, Lasilix, Vesix

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Also known as: Furosemide

Description

Lasix is a potent diuretic. It inhibits sodium and chloride absorption in the ascending limb of Henle's loop and in both the proximal and distal tubules. The high degree of efficacy is due to this unique site of action. The action on the distal tubule is independent of any inhibitory effect on carbonic anhydrase or aldosterone.

Frusemide may promote diuresis in cases which have previously proved resistant to other diuretics.

Frusemide has no significant pharmacological effects other than on renal function.

Dosage

Infants and Children. The usual initial dose of oral Lasix for infants and children is 2mg/kg body weight given as a single dose. If the diuretic response is not satisfactory, the dose may be increased by 1 to 2 mg/kg no sooner than 6 to 8 hours after the previous dose. Doses of greater than 6 mg/kg body weight are not recommended.

For maintenance therapy in infants and children, the dose should be adjusted to the minimum effective level.

Lasix Oral Solution is filled under nitrogen. Use within 3 weeks of opening bottle.

Overdose

In case of a Lasix overdose visit your doctor or health care provider immediately. Symptoms of a Lasix overdose include fainting, tinnitus, confusion, weakness, lightheadedness, lack of appetite.

Storage

Keep this medicine in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away unused furosemide solution after 90 days. Throw away any medicine that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medicine.

Side effects

The most common side effects associated with Lasix are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Caution should be exercised and the risks and benefits of combining risperidone with Lasix or other potent diuretics should be considered prior to the decision to treat. In the risperidone placebo-controlled trials in elderly patients with dementia, a higher incidence of mortality was observed in patients treated with frusemide plus risperidone (7.3% ; mean age 89 years, range 75 to 97) compared to treatment with risperidone alone (3.1% ; mean age 84 years, range 70 to 96) or frusemide alone (4.1% ; mean age 80 years, range 67 to 90). Concomitant use of risperidone with other diuretics (mainly thiazide diuretics used in low doses) was not associated with similar mortality findings. No pathophysiological mechanism has been identified to explain this finding and no consistent pattern for cause of death was observed. Nevertheless, caution is advised. Irrespective of treatment, dehydration was an overall risk factor for mortality and should, therefore, be carefully avoided in elderly patients with dementia.

Rigid sodium restriction is conducive to both hyponatraemia and hypokalaemia, thus strict restriction of sodium intake is not advisable in patients receiving frusemide.

Frusemide should be used with care, especially in the initial stages, in patients with impairment of micturition (e.g. prostatic hypertrophy). Urinary outflow must be secured. In patients with a partial obstruction of urinary outflow (e.g. in patients with bladder-emptying disorders, prostatic hyperplasia or narrowing of the urethra), increased production of urine may provoke or aggravate complaints. Thus, these patients require careful monitoring.

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Interleukin-18 increases TLR4 and mannose receptor expression and modulates cytokine production in human monocytes. Reported is a case of acute infection thought to be of odontogenic origin. As the content of saturated fatty acids in margarine is lower than in butter, the former product was for a long time considered as healthier. This study was performed to observe the effects of Zishenpingchan granule on neurobehavioral manifestations and the activity and gene expression of striatal dopamine D1 and D2 receptors of rats with levodopa-induced dyskinesias (LID). Very few cases of this tumour affecting the tendon sheath have been reported so far. To study the effects of different concentrations of Allium Mongolicum Regel polysaccharides on the generation of signal molecules of sheep peripheral blood lymphocytes in vitro. In the past 1-2 years, there have been a number of publications that promise to make a major difference in patient management and outcome in heart failure. All of them had previous surgery due to rhumatismal heart disease .The surgery was emergent in 3 cases and urgent in 1 case. Evidence was presented that the pulp plays a major role in caries susceptibility.

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However, the effects of different curve severity on the correlation have not been studied in depth. Immunobiology of human uteroplacental macrophages--friend and foe?. Influence of working length and foraminal enlargement on foramen morphology and sealing ability. Progress testing is a valid and reliable tool to assess growth in knowledge longitudinally over the duration of a dental programme. Distal radius and forearm fractures are injuries that are frequently seen in trauma surgery outpatient clinics. It is caused primarily by dental trauma, orthodontic treatment, or dental bleaching. Thus, defining the mechanisms of virus-induced membrane modifications is essential for both understanding virus replication and development of novel approaches to virus inhibition. Overall, our data suggest that the right DLPFC plays a causal role in explicit judgment of facial attractiveness. Compatibility of pIJ487 and pSG1912-1 plasmids and incompatibility of the latter and pWHM4 was shown. Using the absorption curves the band is resolved into two exciton components.

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However, the recent identification of protein complexes producing matrix polysaccharides, and those supporting the synthesis and distribution of a grass-specific hemicellulose are advancing our understanding of the functional contribution of the plant secretory pathway in cell wall biosynthesis. Are we sending the wrong message when we ask health care workers to wash their hands?. Group diagnostic decisions may be more costly, but more appropriate. The aim of a better quality of life may represent a reasonable indication to surgery. Effectiveness of intensive healthcare waste management training model among health professionals at teaching hospitals of Pakistan: a quasi-experimental study. We also highlight the role of the ethanol-inducible cytochrome P450-2E1 (CYP2E1) in some of these PTM changes. Clinical significance of percutaneous endoscopic gastrostomy for patients with severe craniocerebral injury. Remote DWI lesions may be an epiphenomenon associated with the underlying microvascular pathogenesis. The time of LIN-29 appearance in the hypodermis is controlled by the heterochronic gene pathway: LIN-29 accumulates in the hypodermis abnormally early, during the third larval stage, in loss-of-function lin-14, lin-28 and lin-42 mutants, and fails to accumulate in hypodermis of lin-4 mutants.

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