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Labetalol

Labetalol is used to treat high blood pressure. Labetalol is in a class of medications called beta blockers. It works by relaxing blood vessels and slowing heart rate to improve blood flow and decrease blood pressure.

Other names for this medication:
Albetol, Ascool, Biascor, Hybloc, Ibidomide, Ipolab, Labetalol, Labetaloli, Labetalolo, Labetalolum, Normadate, Normodyne, Normozide, Presolol, Resporito

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Description

Labetalol is a drug which is used for treating high blood pressure. It is related to carvedilol (Coreg). Nerves that are part of the adrenergic nervous system travel to most arteries where they release an adrenergic chemical norepinephrine. The norepinephrine attaches to receptors on the muscles of the arteries and causes the muscles to contract, narrowing the arteries, and increasing the blood pressure. Labetalol blocks receptors of the adrenergic nervous system. When Labetalol attaches to and blocks the receptors, the arterial muscles relax, and the arteries expand, resulting in a fall in blood pressure. Generic name of Labetalol is Labetalol. Labetalol is also known as Labetalol, Normodyne. Brand name of Labetalol is Labetalol.

Dosage

Take this medicine with food or milk. If you want to achieve most effective results do not stop taking Labetalol suddenly.

Overdose

If you overdose Labetalol and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Labetalol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Labetalol if you are allergic to Labetalol components. Be careful with Labetalol if you're pregnant or you plan to have a baby, or you are a nursing mother. Be careful with Labetalol if you have a history of liver problems, heart problems, pheochromocytoma, diabetes, any allergies. Do not take Labetalol if you have a lung disease (asthma, COPD), advanced heart block, severe bradycardia, severe heart failure, post-CABG surgery. This drug may make you dizzy for up to 3 hours after it is given. You should remain lying down during this time period in order to prevent falls. You should get up slowly when rising from a seated or lying position. Be very careful if you are driving machine. Avoid alcohol. Diabetic patients should be careful with Labetalol. Do not stop taking Labetalol suddenly.

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Remembering the best and worst of times: memories for extreme outcomes bias risky decisions. Acute appendicitis after prior appendicectomy is highly difficult to diagnose, especially in face of definite history of appendicectomy and presence of appendicectomy scar in the right iliac fossa. Inclusion of NaCl reduced morphological inconsistencies and minimized process variability. Both sperm count and daily sperm production were significantly decreased by DEHP treatment at doses of 600 and 900 mg/kg. A proposed framework for an appropriate evaluation scheme for microorganisms as novel foods with a health claim in Europe. Transaortic septal myectomy is the gold standard for the treatment of symptomatic hypertrophic obstructive cardiomyopathy that is refractory to medical therapy. muricata (Willd.) Chakravarty) has been reported to possess many benefits and medicinal properties. Pharmacokinetics of Certoparin During In Vitro and In Vivo Dialysis.

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The results suggest that administration of NMD-Lipo has no sedative or muscle relaxant effect in animals, since there was no reduction in the number of crossings, grooming and rearings. Multiple sclerosis: Drug-enhanced remyelination in a multiple sclerosis model. However, the influence of host cell cholesterol homeostasis on IAV infection is largely unknown. Data from the Veneto Region suggest that the increase in PTMC is due to several factors: increased preoperative diagnosis, total gland removal, extensive histological examination. Particle size reduction, specific surface area increase, crystalline structure decomposition and bond breakage have been identified as the main processes occurring during the mechanochemical operations in the studies.

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Regression analysis revealed a high correlation between ATM protein levels and SF2 for primary glioma cell strains, but not for established GBM cell lines. However, to capture more precise sequence-structure relations, no method reported to date combines structure-based profiles, and sequence-based profiles based on evolutionary information. Based on these and other findings (1-5), we discuss the possibility that Mphi may play as important a role in presenting T-cell communication signals to the cells of the immune system as they do in presenting antigen. The authors have proposed a temporally diffeomorphic motion estimation method in which a spatiotemporal transformation is estimated by optimization of a registration energy functional of the velocity field in their earlier work. Bivalve larvae abundances were very high throughout the year: 18,550 m(-3) in average. The focus of this review is to critically evaluate several mechanisms that may come into play for the interpretation of the in vivo pharmacokinetic data of drugs co-administered with BioA.

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Circulating EMP and PMP, known to be indicators and mediators of vascular injury, were not significantly altered in men with AS who did not have classical cardiovascular risk factors. Variation in food stoichiometry affects individual performance and population dynamics, but it is also likely that species with different life histories should differ in their sensitivity to food stoichiometry. Characteristics of muscle fibers in rats with limb movements during sleep after spinal cord injury. The use of dietary supplements in sports is widespread as athletes are continuously searching for strategies to increase performance at the highest level. erectum extract was administered per os in the dose of 50 mg/kg for 7 days. Copper storage disease had been diagnosed previously on the basis of high hepatic copper concentration. Primary patient-derived tumorsphere growth was significantly inhibited by MK-2206. In zebrafish, as fish experience more and more danger, neurons in the ventral habenula (vHb) showed tonic increase in the activity to the presented cue and activated serotonergic neurons in the median raphe (MR).

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Construction project resources (e.g., regulatory guidance and room data sheets) can mask or obscure the meaning of infection control issues. After mutagenization of conidiospores with high doses of UV, we isolated 20 mutants with defects in ascospore formation. The PYL family has 14 members in Arabidopsis, 13 of which have been demonstrated to function as ABA receptors. The microvascular coronary flow velocity reserve (CFVR) was tested for endothelium-dependent (acetylcholine) and -independent (adenosine) stimuli by intravascular Doppler flow-wire. In Experiment 2, a dry maze task was conducted on a circular open field which contained 16 holes arranged symmetrically and which was put on the same height as the surface of the water maze. Advantages and disadvantages of PET and SPECT in a busy clinical practice. There was no evidence for a social relationships buffering effect.

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The system described here provides a more comprehensive picture of the combinatorial control mechanisms orchestrating skeletal muscle growth in a salmonid, leading to a better understanding of myogenesis in this species and across Vertebrata more generally. We retrospectively reviewed the prenatal US database at our institution for the period between January 2012 and December 2013. Frequency of different genotypes among patients was assessed according to gender, age and geographical region at the time of sampling. Hopefully, the information obtained may lead to a better understanding of the pathogenesis and development of novel therapeutic strategies for this systemic autoimmune disease. To investigate the association between home environment resources and the school performance of children from a public school in Belo Horizonte, Brazil, enrolled in the fourth year of the second cycle of Elementary School. We examined the rate of possible hypotension-related adverse events (diagnosis codes for hypotension, syncope, dizziness, fractures, and other injuries) per 10,000 person-days for men who began therapy with alpha1 antagonists and for a random sample of nonusers, stratified by prior use of other antihypertensive agents. The action of peptides against fungal cell membranes was examined by treating prepared protoplasts of C. Moreover, induced tyrosine phosphorylation of TH1 has been found by EGF and estrogen treatments.

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Other variables, such as the thickness of the endometrium, were found to have no prognostic value. Here we show that the non-catalytic domains of Drosophila katanin regulate its abundance and activity in living cells. Evaluation of the pharmacokinetics and ocular tolerance of a microemulsion containing tacrolimus. When comparing patients with the same TNM (tumor, node, metastasis) stages, no significant difference in the 5-year survival rates was apparent. These results suggest that the reaction, which occurs in the midgut of intoxicated insects, is determined by the interplay between passive toxic action and the active host healing response, in a toxin concentration-dependent manner. Interaction between calf thymus DNA and cationic bottle-brush copolymers: equilibrium and stopped-flow kinetic studies.

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The effect of various ultrasonic tooth cleaning devices on dental filling materials. Tissue-specific deletion of the gene for NADPH-cytochrome P450 (P450) reductase (CPR), the essential electron donor to all microsomal P450 enzymes, in either liver or intestine, leads to upregulation of many P450 genes in the tissue with the Cpr deletion. Staging anterior cervical decompression and fusion with posterior cervical instrumented fusion 1 week apart does not decrease the incidence of perioperative complications. Total cholesterol, high-density lipoprotein (HDL) cholesterol, low-density lipoprotein cholesterol, and triglycerides were measured in plasma. Statistical measures (accuracy for the occurrence model and mean squared error for the abundance model) were used to evaluate the models performance. As this association has been found in three cohort studies in various clinical settings, further investigation of this association is warranted. Isoxyl and Thiacetazone are two antitubercular prodrugs formerly used in the clinical treatment of tuberculosis. Results of a survey on albumin use in clinical practice in intensive care units. Takayasu arteritis: Association with mesangioproliferative glomerulonephritis in a 9-year-old child.

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The effects on survival of such psychosocial interventions need to be tested in a randomized controlled study. The major unit length is 11 kb, but variant length units at 10.4, 10.7 and 11.3 kb were found as minor forms. Preparation and characterization of Zr-N-codoped TiO2 nano-photocatalyst and its activity enhanced-mechanism. Elevated levels of UBF were also observed in the hepatic tumors of HBx transgenic mice. Mice immunized with allogeneic cells exhibited negative delayed footpad reaction and positive macrophage migration inhibition. This study provides an insight into this complicated decision making process for a poorly soluble human immunodeficiency virus (HIV) protease inhibitor based upon in vivo test results.

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Submassive PE is identified by the findings of right ventricular dysfunction by physical examination or imaging, or by elevations in serum troponin or brain-type natriuretic peptide in the context of acute PE. The analysis indicates that receptor tyrosine kinases are functionally compartmentalized into distinct collaborative groups distinguished by activation and intracellular localization of SRC-family kinases, especially FYN and LYN. Protection from Cigarette Smoke-Induced Lung Dysfunction and Damage by H2 Relaxin (Serelaxin). There is very little information regarding blood changes during the challenge of phospholipase D (PLD) in goats. Enforced ATP futile cycling increases specific productivity and yield of anaerobic lactate production in Escherichia coli. The behavioural threshold for this tone was determined using a modified tracking procedure and found to be similar to that reported using cochlear microphonic potentials. We conducted a mixed-methods pilot study to assess the feasibility of using particular measures of pain, pain coping and quality of life within semi-structured interviews with boys and young men with Duchenne Muscular Dystrophy and a postal survey of their parents.

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Effects of cilazapril on renal haemodynamics and function in hypertensive patients: a randomised controlled study versus hydrochlorothiazide. In this Review, I propose that genetic mutations associated with OA can be placed on a continuum. Although the release of aromatic compounds from plant biomass by fungi has been studied extensively, relatively little attention has been given to the metabolic pathways that convert the resulting aromatic monomers. Early endovascular treatment of superior mesenteric occlusion secondary to thromboemboli. The objective of our study was to describe the effects of an intravenous Omega-3 bolus before reperfusion in a rat model of myocardial IR. However, such patterns are often highly variable across compounds and lack robustness.

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Additionally, using the fusion technique to guide interventional procedures enhanced the workflow, and required much less radiation exposure and contrast medium use, thus helping to reduce potential risks and increase treatment safety. Screening using a questionnaire and cotinine detection appeared to constitute a simple, inexpensive, rapid and reliable test. Total ribonucleic acid extracted from these samples was subjected to reverse transcription and two separate sets of multiple polymerase chain reaction. short palpebral fissures, short, upturned nose, hypoplastic philtrum, hypoplastic maxilla). The quest of the human proteome and the missing proteins: digging deeper. Unlike pharmacologic inhibitors, the genetic approach described here allows for upregulation as well as inhibition of the mTORC1 pathway and is highly selective for the therapeutic T cells without affecting systemic mTORC1 functions. With the development of molecular biology, etiologic classification--a system unrelated to that of clinical appearance--was begun.

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Glutamate has been measured using different methods to determine its role under normal and pathological conditions. The diagnosis of superficial siderosis of the central nervous system was made by these findings of magnetic resonance image and cerebrospinal fluid. Subacute peritonitis significantly elevated the levels of nitrate, nitrite and TBARS in the plasma and decreased glutathione peroxidase activity in the kidneys. Group housing and nest building only slightly ameliorate the cold stress of typical housing in female C57BL/6J mice. Dominant hemisphere lateralization of cortical parasympathetic control as revealed by frontotemporal dementia. Several human pregnancy supplementation trials with n-3 fatty acids have shown a significant reduction in the incidence of premature deliver and increased birth weight associated with increased gestational duration. The current results showed that non-adenocarcinoma histology, elevated serum CEA at recurrence and no systemic chemotherapy were independent unfavourable post-recurrence prognostic factors. Further research on counselor techniques for promoting commitment language among juvenile gang offenders is needed.

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Two-generation diet-induced obesity model producing mice with increased amount of body fat in early adulthood. What factors influence help-seeking for hearing impairment and hearing aid adoption in older adults?. The Ethics of Chronic Dialysis for the Older Patient: Time to Reevaluate the Norms. Our findings and the issues raised are considered for general dental practitioners, for people residing in the authority, and for managers and policy makers. Two Draft Genome Sequences of a New Serovar of Salmonella enterica, Serovar Lubbock. To determine the extent to which immaturity of hepatic microsomal enzyme activity might contribute to physiological jaundice. Spinal cord injury is a rare finding in patients presenting with drug overdose. This study showed that multiple factors contribute to the challenge of cervical cancer screening and treatment in Tanzania. The final diagnosis was based on colonoscopic findings and histopathologic results categorized into benign, premalignant, or malignant. The strategies employed in vaccinology have improved since the seminal work of Edward Jenner in the eighteenth century.

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Despite a trend toward a positive association between BMI and AAA presence, the reason why BMI is not associated with AAA growth (suggested in the present review) is unclear. A total of eight children (seven with neurodevelopmental disorders and all inpatients) with target behaviors refractory to other treatments were selected after parental informed consent. In Experiment 1, we tested whether the gaze direction of the speaker modulates cortical responses to infant-direct speech. Both Caco-2 and T84 IECs can be maintained in the VDC under these conditions without any apparent detrimental effects on cell survival or monolayer integrity. The aim of this study was to determine the prevalence of RIS at a university hospital in a region with a high prevalence for MS and describe the long-term prognosis of the identified patients. Subsequently, validity and reliability studies were conducted (1(st) compilation), followed by retesting seven days later (2(nd) compilation). Body weight, mean arterial pressure, heart rate, body temperature, NGAL levels, and cozaar type of medication renal histology were compared across groups. We have discovered a novel class of heterocyclic sulfonamides that act as antagonists of the S1P1 receptor. Additionally, high vaccination card availability and high participation in VWA among those caregivers aware of it in 2011 suggest public trust in the EPI program in the municipality.

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We describe the consideration of Bezold Jarisch reflex and amniotic fluid embolism as most appropriate in this case. A retrospective review of medical records was conducted for 83 esophageal cancer patients who underwent robotic esophagectomy at our institute from December 2009 to December 2012. Precise knowledge of genetic aspects of disease susceptibility is important for improvement of public health. Treatment was continued for four to six cycles, except in cases of progressive disease or toxicity, and patient refusal. The influence of additional predictor variables (age, sex, perceived social support) and type of disorder as a moderator variable was also tested. Because reappraisal is thought to be supported by linearly developing prefrontal regions, one prediction is that reappraisal ability develops linearly.

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The 78-82 kDa protein represented the non-glycosylated precursor which was resistant to the enzymes. Arthroscopic treatment of medial meniscal cyst has replaced the traditional method, which could retain the normal meniscus as much as possible and repair the meniscus injury simultaneously, as well as get a good curative effect and a good recovery of knee function. United vasotec cost States Indigenous Populations and Dementia: Is There a Case for Culture-based Psychosocial Interventions?. BDNF is therefore required for expression of normal respiratory behavior in newborn animals. By means of microsurgery the spinal tumor was completely removed.

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Data from 70 significant papers were reviewed in order to define the character of reparability and the possibility of alternative techniques in the management of MRCT. Kainate produces concentration-dependent elevation of glutamate release but not cGMP levels in cultured neuron. This bias could be due to a reference point effect, in which people estimate more space between places close to them than far from them, or to representational pseudoneglect, in which neurologically intact individuals favor the left side of space when asked to image a scene. Detailed demographic and clinical data during the study period were collected along with PD related complications. Labelled regions appeared to correspond to stress-related sites. Immediate treatment with ZA prevented bone loss compared with delayed treatment in postmenopausal women receiving letrozole and these differences were maintained at 5 years.

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In addition, the effects of gender and speech rate elicitation techniques (metronome-controlled, self-controlled) were examined. Medical history was significant for hypertension and medications included captopril, metoprolol and aspirin. We evaluated cranial ultrasound (cUS) scans from term Ugandan infants with and without NE for evidence of brain injury. They fulfill important roles in protein folding and the protection of cells from stress. The 2011 FAO Expert Consultation recognized that the Digestible Indispensable Amino Acid Score (DIAAS) was superior to the PDCAAS for determining protein quality. Analysis of melanocyte precursors in Nf1 mutants reveals that MGF/KIT signaling promotes directed cell migration independent of its function in cell survival. Ion channels encoding genes are acquiring increasing relevance in oncological translational studies, representing new candidates for molecular diagnostic and therapeutic purposes. The ratio of the LH-FSH areas under the curves favored FSH in the amiloride 5mg tablets early follicular phase and LH at midcycle and luteal phase. Subjective hearing impairment predicted clinically assessed hearing loss, suggesting that there is cause for concern as regards the future development of hearing in young to middle-aged people. Overdiagnosing of femoroacetabular impingement: correlation between clinical presentation and computed tomography in symptomatic patients.

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Activatable cell-penetrating peptides are of great interest in drug delivery because of their enhanced selectivity which can be controlled by the external stimuli that trigger their activation. P815 cells previously co-cultured with Salmonella-infected macrophages became targets for cytotoxic T lymphocytes isolated from Salmonella-infected BALB/c mice. In contrast, increases in lung cell polyamines required for hypoxic pulmonary vascular disease can be attributed to augmented transmembrane polyamine transport which may, in turn, be the result of hypoxia-related decreases in the activity of the initial and generally rate-limiting enzyme in de novo polyamine synthesis, ornithine decarboxylase (ODC). The virulence mechanisms of Xoc are not entirely clear and control measures for BLS are poorly developed. In twelve chronically catheterized fetal lambs we measured lung liquid volume at 140 days gestation (term is vasotec generic name 147 days) and then delivered the fetuses by Caesarean section under maternal spinal anaesthesia. Structural and dynamical properties of chlorinated hydrocarbons studied with resonant inelastic x-ray scattering. The decrease of lifetime of experimental rats exposed to electromagnetic fields with different parameters and development of tumours (in one set of experiments) was found. In the first experiment the results show the progression of improvement in reliable and unique parameter estimation through the use of each tool to reduce and remove non-identifiability. Lymphoma, however, is the most frequent metastatic tumor in this location. The aim of the present study is to review the scientific evidence on the mental health consequences of immigration detention for adult survivors of torture.

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The modified SHA coding allowed financing to be mapped to specific immunisation activities, and could be used for standardised, resource tracking compatible with National Health Accounts (NHA). To date, only two of these genes, NS4B and NS5A, have been trans-complemented, leading to suggestions that other replicase genes work only in cis. A biochemical view: vitamin D levels do not affect in vitro fertilization outcomes following the transfer of euploid blastocysts. We retrospectively reviewed the records of 100 patients, hospitalized and treated in the department of ophthalmology at the Mohamed Taher Maamouri university medical center in Nabeul, Tunisia for an open globe injury between January 2006 and November 2013. We present a case of dramatic reactivation of clinical disease activity with newly emerging pseudotumoral lesions in a patient who stopped treatment due to pregnancy. Ex vivo human corneal epithelial cell expansion from a xeno-feeder-free system. It has been postulated that immigrant children are at increased risk of mental health problems. The local production of pro-inflammatory anaphylatoxins C3a and C5a was crucial to the tumor response to radiotherapy and concomitant stimulation of tumor-specific immunity. The core promoter of eukaryotic coding and non-coding genes that are transcribed by RNA polymerase II (RNAP II) is composed of DNA elements surrounding the transcription start site. Detailed methods are presented for expression, purification, and release testing of SARS recombinant spike protein antigen, followed by adjuvant formulation and animal testing.

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Seven near-isogenic barley lines, differing for three independent mutant genes, were grown in 15 environments in Spain. In this study, we developed an immunoassay for measuring antibodies against recombinant PM/Scl-100 and PM/Scl-75 polypeptides, which are the two major targets of the complex, and we investigated their side effects of enalapril maleate 20 mg presence in 600 Japanese patients with various systemic autoimmune conditions. A three-dimensional motion analyzer was used to measure arm and trunk movements. In the exploration box test, CRA 1000 (1.25 mg/kg) had an anxiolytic effect on rat exploratory behaviour both in intact rats and after lesioning of the projections of locus coeruleus by DSP-4 (50 mg/kg) treatment. Value of apexcardiography for the timing of left ventricular events in man.

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Additionally, CSPGs create a non-permissive milieu for cell replacement activities by limiting cell migration, survival and differentiation. Ventral transpalpebral anterior orbitotomy is a simple procedure that allows easy access to the ventral anterior orbit to allow for removal of diseased tissues or to facilitate drainage of abscessation. Patients with hematological neoplasms transferred to an Intensive Care Unit (ICU) for a life-threatening complication have a poor outcome. Assessment of ergonomic strain during robotic surgery indicates there is a need for intervention. Aortic valve allografts are able to induce a donor-reactive immune response that is related to early graft destruction and incompetence.

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Effect of platelet activating factor receptor drug cozaar side effects at spinal cord neurocyte membrane on secondary damage after spinal cord injury. The excitotoxic hypothesis of neurodegeneration has further stimulated our interest towards the study of the interactions between DA and other neurotransmitters into the basal ganglia. Gemcitabine-induced pseudocellulitis in a patient with non-small cell lung carcinoma. The appearance, texture, and color of the flaps were similar to normal skin. Helen Flanders Dunbar (1902-1959) and a holistic approach to psychosomatic problems. In addition to single-lung ventilation (SLV), positive-pressure CO2 insufflation is mandatory for totally endoscopic coronary artery bypass grafting. Model of isotachophoresis (displacement electrophoresis) in tapered capillaries. Long-term clinical course and outcome of schizophrenia in rural Ethiopia: 10-year follow-up of a population-based cohort.

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