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Aprical (Nifedipine)

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Aprical is a dihydropyridine calcium channel blocker. Aprical is used to: treat high blood pressure (hypertension), prevent chronic stable angina (chest pain). Aprical was the first calcium channel blocker to be shown to significantly reduce the development of new overt heart failure in patients with coronary artery disease. Excellent blood-pressure control in recent clinical trials has been shown to result in significant protection against stroke. Aprical works by opening up blood vessels in the body to lower blood pressure and improve the supply of blood and oxygen to the heart. Calcium channel blockers do not change the amount of calcium in your blood or bones.

Other names for this medication:
Adalate, Amarkor, Anpect, Atanaal, Atenerate, Bresben, Buconif, Calcheck, Cardipin, Carditas, Cardules, Citilat, Cobalat, Conetrin, Corotrend, Farmalat, Fenamon, Ficor, Jutadilat, Milfadin, Nedipin, Nidilat, Nidipine, Nifangin, Nifatenol, Nifecardia, Nifed, Nifedalat, Nifediac, Nifedicor, Nifedin, Nifedine, Nifedipin, Nifedipina, Nifedipress, Nifehexal, Nifelat, Nifezzard, Nifical, Oxcord, Pressolat, Tenif, Tensomax, Valni, Zenusin

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Also known as: Nifedipine


Aprical is a perfect remedy in struggle against hypertension or high blood pressure, angina or chest pain. Aprical acts by relaxing blood vessels (such as veins and arteries), which makes it easier for the heart to pump and reduces its workload. Aprical is also known as Nifedipine, Nicardia, Nifedical, Procardia. Generic name of Aprical is Nifedipine. Brand names of Aprical are Aprical CC, Procardia, Procardia XL.


Aprical should be taken orally with or without food. It is better to take Aprical at the same time every day. Take on an empty stomach. Avoid grapefruit juice during treatment with Aprical. If you want to achieve most effective results do not stop taking Aprical suddenly.


If you overdose Aprical and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Aprical are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Aprical if you are allergic to Aprical components. Do not take Aprical if you're pregnant or you plan to have a baby, or you are a nursing mother. Aprical can harm your baby. Do not use Aprical in combination with salt substitutes or potassium supplements. If you want to achieve most effective results without any side effects it is better to avoid alcohol. Avoid grapefruit juice during treatment with Aprical. Try to be careful using Aprical if you suffer from kidney disease, liver disease, diseases of the heart or blood vessels (sick sinus syndrome), aortic stenosis, heart failure, low blood pressure, or coronary artery disease. Do not stop taking Aprical suddenly.

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Red cell distribution width is a measure of deviation of the volume of red blood cells. This study investigated the presence of serum antinuclear antibodies (ANA) profile and direct immunofluorescence (DIF) evaluation in elderly Thai patients with red and white oral lesions. The aim of this study was to assess the prognostic value of myocardial viability recognized as a contractile response to vasodilator stimulation in patients with left ventricular dysfunction in a large scale, prospective, multicentre, observational study. Destruction of peripheral C-fibers does not alter subsequent vagus nerve stimulation-induced seizure suppression in rats. The mice were divided into six groups: one group received intraperitoneal injections of normal saline, another group received alcoholic saline which was used as the vehicle of pineal indoles, and the remaining groups received respectively hydroxyindoleacetic acid (HIAA), melatonin (MEL), methoxytryptamine (MTA) and methoxytryptophol (MTP). Our objectives were to review the strengths and limitations of RID methods, to discuss what is known about the impact of various factors on results, and to summarize contributions of model-based compartmental analysis to assessing VA status.

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Treatment of chemotherapy-induced leucopenia in patients with malignant tumor by Chinese herbal medicine: a systematic review and meta-analysis of randomized clinical trials. Pretreatment with protein kinase C inhibitors, H-7 or staurosporine, partially suppressed the PAI activity induced by plasmin. Magnesium-deficient high-fat diet: effects on adiposity, lipid profile and insulin sensitivity in growing rats. The pretreatment of MSCs with Ang II improved the outcome of MSC-based therapy for MI via the mechanisms of enhancing the paracrine production of VEGF, angiogenesis, and gap junction formation. The relationship between clinical attachment loss and the duration of insulin-dependent diabetes mellitus (IDDM) in children and adolescents.

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