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Anfuramide (Furosemide)
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Anfuramide

Anfuramide is a loop diuretic (water pill) that makes you urinate more. It works in the kidneys to get rid of extra water and electrolytes (like sodium and potassium), which helps with swelling and lowers blood pressure. Anfuramide can be taken once or twice a day for swelling. Adults typically start with 20 mg to 80 mg per dose. Some adults with really bad swelling problems may take up to 600 mg in a day.

Other names for this medication:
Aldalix, Anfuramide, Ansemid, Betasemid, Foliront, Frusemide, Frusenex, Furantral, Furesis, Furetic, Furide, Furocot, Furosemide, Furovet, Furoxem, Furozenol, Fursemid, Furtenk, Fusix, Inclens, Intermed, Jufurix, Lasilacton, Lasilactone, Lasiletten, Lasilix, Salix, Vesix

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Also known as: Furosemide

Description

Anfuramide prevents excessive edema (fluid retention) in people with kidney disorder (nephrotic syndrome), heart failure, cirrhosis and liver disease. It is also used for the treatment of high blood pressure (hypertension), high levels of potassium (hyperkalemia), calcium (hypercalcemia), and magnesium (hypermagnesemia). The active component, Furosemide, is a potent loop diuretic (water pill) that eliminates water and salt from the body. Furosemide works by blocking the absorption of sodium, chloride, and water from the filtered fluid in the kidney tubules, causing a profound increase in the output of urine (diuresis). Anfuramide starts to act within one hour after oral administration, and the effect lasts for about 6-8 hours.

Dosage

Adults. The usual initial daily dose is 20 to 80 mg given as a single dose. If the diuretic response to a single dose of 20 to 80 mg is not satisfactory, increase this dose by increments of 20 to 40 mg, not sooner than 6 to 8 hours after the previous dose, until the desired diuretic effect is obtained. This individually determined dose should be given once or twice (e.g. at 8 am and 2 pm) daily. The dose of Lasix may be carefully titrated up to 400 mg/day (except in advanced renal failure) in those patients with severe clinical oedematous states. The mobilisation of oedema may be most efficiently and safely accomplished by giving Lasix on 2 to 4 consecutive days each week.

When doses exceeding 80 mg/day are given for prolonged periods, careful clinical laboratory observations are particularly advisable.

Overdose

In case of a Anfuramide overdose visit your doctor or health care provider immediately. Symptoms of a Anfuramide overdose include fainting, tinnitus, confusion, weakness, lightheadedness, lack of appetite.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Anfuramide are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

In children, urge to defecate, complaints of abdominal pain and cramping have been reported after IV frusemide. An association of these symptoms with a low serum calcium and/or a low calcium/protein ratio is possible.

Reversible elevations of blood urea may be seen. These have been observed in association with dehydration, which should be avoided, particularly in patients with renal insufficiency.

Frusemide increases cholesterol and triglycerides short-term. It is not clear whether this effect persists long-term, however, the current evidence does not indicate this.

As with many other drugs, patients should be observed regularly for the possible occurrence of blood dyscrasias, liver damage, or other idiosyncratic reactions.

Renal calcifications (from barely visible on X-ray to staghorn) have occurred in some severely premature infants treated with intravenous Lasix for oedema due to patent ductus arteriosus and hyaline membrane disease. The concurrent use of chlorothiazides has been reported to decrease hypercalciuria and to dissolve some calculi.

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These later parameters have been estimated by calibration on respirometric data, thus demonstrating that coupling analyses of OM fractions in initial wastes and respirometric tests permit the simulation of the biodegradation of various type of waste. Previous reports demonstrated that platelet-derived growth factor-AA (PDGF-AA) enhanced the formation of dermal condensates in hair follicular development. In vivo monitoring of serum protein cross linking in patients with diabetes mellitus. Clinical trials of smoking cessation interventions published in English or Chinese were extracted from an electronic search of PubMed and WanFang databases. At presentation, all patients with LAHS-AI had positive laboratory tests for autoimmune diseases, most commonly for systemic lupus erythematosus while these tests were negative in LAHS-VI. Ionic basis for membrane potential changes induced by hypoosmotic stress in guinea-pig ventricular myocytes. From this normative group, 47 randomly selected chinchillas were exposed to various high level (150-, 155-, and 160-db peak SPL) impulse noises. Bacterial genotoxins, produced by several Gram-negative bacteria, induce DNA damage in the target cells. Nevertheless, the cardiac fibroblasts transfected with miRNA-29a mimics obtained the opposite expression result.

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Our objective was to study the association between IVF, both with and without oocyte donation, and maternal and perinatal outcomes in a population of older women. Intraoperative neurophysiological monitoring improves outcome in neurosurgery. Jesterone and hydroxy-jesterone are novel highly functionalized cyclohexenone epoxides isolated from a newly described endophytic fungal species--Pestalotiopsis jesteri. Production of novel fusarielins by ectopic activation of the polyketide synthase 9 cluster in Fusarium graminearum. aeruginosa isolates attached to immobilized collagen type I or type II in the presence of monosaccharides, which could serve as blockers of bacterial receptors. Breast reduction in patients with a history of lumpectomy and irradiation is controversial because of a heightened risk of infection and wound healing complications. To validate the potential for oral administration of the telmisartan/L-PGDS complex in vivo, the pharmacokinetic and pharmacodynamic profiles were assessed in spontaneous hypertensive rats. Inherited Magnetic Maps in Salmon and the Role of Geomagnetic Change. Quantitative structure-property relationships (QSPRs), based only on a single-parameter, are proposed for the prediction of physico-chemical properties, namely, aqueous solubility (logSW), octanol-water partition coefficient (logKOW) and octanol-air partition coefficient (logKOA) of polychloronaphthalenes (PCNs) including all the 75 chloronaphthalene congeners. Using the Ph (I) gene stock, we could demonstrate homoeologous pairing between the wheat and Haynaldia villosa chromosomes.

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Bcl-2 family protein behavior in frontotemporal dementia implies vascular involvement. Isolation and characterization of plant growth promoting traits of a rhizobacteria: Pantoea agglomerans lma2. Although the therapeutic effect of DS is likely associated with anti-inflammatory activity, the precise underlying mechanisms are largely unknown. Since the in vivo functional and structural status of endothelial cells correlates with the applied shear stress, we developed a computer-controlled perfusion system to seed and culture cells on PTFE-grafts up to a confluent monolayer under the influence of increasing shear stress. Two cases are presented to highlight the potential immediate clinical implications of comprehensive genomic profiling. Long-term outcomes on spatial hearing, speech recognition and receptive vocabulary after sequential bilateral cochlear implantation in children. Spinal NK1 receptor is upregulated after chronic bladder irritation.

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They occupy habitats defined by the range and variability of their abiotic environment. mobilityRERC state of the science conference: Individualizing pressure ulcer risk and prevention strategies. Tissues from 89 cases of condyloma acuminata, 76 cases of cervical cancer and swabs from 198 cases of normal vaginal were analysed by polymerase chain reaction for HPV infective rate. Investigation on the pleasantness of music perception in monolateral and bilateral cochlear implant users by using neuroelectrical source imaging: a pilot study. Both the contact angels and zeta potentials increased with the increase of degrees of carboxymethylation. Fall in veterinary antibiotics sales positive but small, says VMD. Our study aimed to investigate the effect of Qiwei granules on podocyte lesion in diabetic KK-A(y) mice kidney and its underlying mechanism. Randomised clinical trial of the effects of prolonged-release melatonin, temazepam and zolpidem on slow-wave activity during sleep in healthy people. Spondylocarpotarsal synostosis syndrome (SSS) is an autosomal recessive condition which is characterized by short stature, a carpotarsal coalition and a vertebral fusion, but without any rib anomaly. But neither of three herbicides were mutagenic using TA98 and TA100.

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